Canazole Suspension contains Fluconazole 50 mg per 5 ml, a triazole antifungal used for the treatment and prevention of a variety of fungal infections. It is particularly suitable for children and patients who have difficulty swallowing tablets, offering the same systemic antifungal activity as oral tablets.

Fluconazole works by inhibiting fungal cell membrane synthesis, effectively controlling infections caused by Candida species and other susceptible fungi. The oral suspension provides a measured, easy-to-administer liquid form for accurate dosing in pediatric and adult patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Canazole Suspension is indicated for:

• Oropharyngeal and esophageal candidiasis in children and adults
• Vaginal candidiasis
• Systemic fungal infections caused by susceptible fungi
• Prophylaxis of fungal infections in immunocompromised patients (e.g., undergoing chemotherapy or organ transplantation)

Composition

• Active Ingredient: Fluconazole
• Strength: 50 mg per 5 ml
• Dosage Form: Oral suspension

Mechanism of Action

Fluconazole is a triazole antifungal agent. It:

• Inhibits lanosterol 14α-demethylase, essential for fungal ergosterol synthesis
• Disrupts the fungal cell membrane, causing cell death
• Provides broad-spectrum antifungal coverage against Candida species and other susceptible fungi

This mechanism ensures effective treatment of fungal infections while maintaining safety for human cells.

Dosage & Administration

• Adults: 50–200 mg once daily, based on infection type and severity
• Children: Dose is weight-based; typically 6–12 mg/kg once daily
• Shake the bottle well before use
• Measure the dose accurately using a calibrated oral syringe or cup
• Take with or without food
• Complete the full course to prevent recurrence or resistance
• Dose adjustment may be required for patients with renal impairment

Side Effects

Canazole Suspension is generally well tolerated. Possible side effects include:

• Nausea and vomiting
• Diarrhea or abdominal discomfort
• Headache
• Rash
• Rare: liver enzyme elevation, allergic reactions

Seek medical advice if side effects persist or worsen.

Precautions & Warnings

• Use cautiously in patients with liver or kidney disease
• Monitor liver function for prolonged therapy
• Avoid use with medications that prolong QT interval or interact with CYP3A4
• Not recommended for routine prophylaxis without medical supervision

Drug Interactions

• May interact with warfarin, phenytoin, cyclosporine, or certain statins
• Inform your healthcare provider of all medications and supplements being taken

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly necessary; consult a physician
• Lactation: Avoid breastfeeding or seek medical advice
• Elderly: Monitor renal and liver function; adjust dose if needed
• Pediatrics: Safe with weight-based dosing and supervision

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep the bottle tightly closed
• Keep out of reach of children.