CardiAmlo Tablet 2.5 mg+5 mg is a combination antihypertensive medication containing Bisoprolol Fumarate 2.5 mg and Amlodipine Besilate 5 mg, formulated for effective management of hypertension and related cardiovascular conditions. This dual-action therapy combines a beta-adrenergic blocker (Bisoprolol) with a calcium channel blocker (Amlodipine), providing complementary mechanisms to control blood pressure, reduce cardiac workload, and improve overall cardiovascular health.

The combination is ideal for patients who do not achieve adequate blood pressure control with a single agent. Bisoprolol slows the heart rate and reduces myocardial oxygen demand, while Amlodipine relaxes blood vessels and improves blood flow, resulting in enhanced antihypertensive efficacy and prevention of complications such as heart attack, stroke, and heart failure.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Bisoprolol Fumarate 2.5 mg – selective beta-1 adrenergic receptor blocker

• Amlodipine Besilate 5 mg – long-acting calcium channel blocker

Mechanism of Action

Bisoprolol:

• Selectively blocks beta-1 adrenergic receptors in the heart

• Reduces heart rate, cardiac output, and myocardial oxygen demand

• Helps control tachycardia and arrhythmias associated with hypertension

Amlodipine Besilate:

• Inhibits calcium ion influx in vascular smooth muscle, causing vasodilation

• Reduces peripheral vascular resistance, lowering blood pressure

• Improves coronary blood flow, helping prevent angina attacks

The combination provides dual antihypertensive action, addressing both vascular resistance and cardiac workload, which is particularly effective in patients with moderate to severe hypertension or coexisting angina.

Indications

CardiAmlo Tablet 2.5 mg+5 mg is indicated for:

• Essential hypertension – for patients requiring combination therapy

• Chronic stable angina – to prevent angina attacks and improve exercise tolerance

• Secondary prevention of cardiovascular events in high-risk patients

• Heart rate control in hypertensive patients with tachycardia

• Management of left ventricular dysfunction in select patients

Benefits

• Effective Blood Pressure Control: Addresses both vascular and cardiac mechanisms

• Reduces Cardiovascular Risk: Lowers risk of stroke, heart attack, and heart failure

• Dual Mechanism Therapy: Bisoprolol slows heart rate; Amlodipine relaxes blood vessels

• Relieves Angina Symptoms: Helps prevent chest pain and improves oxygen delivery to the heart

• Convenient Once-Daily Tablet: Enhances adherence to therapy

• Suitable for Combination Therapy: Ideal for patients unresponsive to monotherapy

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Adults: 1 tablet orally once daily, preferably at the same time each day

• Can be taken with or without food

• Dose adjustments may be necessary in elderly patients or those with renal or hepatic impairment

• Regular monitoring of blood pressure, heart rate, and kidney function is recommended

• Do not discontinue therapy abruptly, as this may lead to rebound hypertension or angina exacerbation

Safety and Precautions

• Common side effects: dizziness, fatigue, headache, peripheral edema, or mild palpitations

• Rare side effects: bradycardia, hypotension, bronchospasm, or severe allergic reactions

• Contraindicated in patients with severe bradycardia, heart block, cardiogenic shock, or hypersensitivity

• Use with caution in patients with asthma, diabetes, or severe peripheral vascular disease

• Pregnant or breastfeeding women should take only under medical supervision

• Inform your physician about all medications being taken to avoid interactions.