Cefa-4 Injection 1 gm/vial contains Cefepime Hydrochloride, a fourth-generation cephalosporin antibiotic used for the treatment of a wide range of bacterial infections. Cefepime is highly effective against both Gram-positive and Gram-negative bacteria, including multi-drug resistant strains. It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death.

This injectable formulation is ideal for severe infections, hospitalized patients, and situations where oral antibiotics are unsuitable or ineffective. Cefa-4 provides rapid and reliable antibacterial action, helping to control infections effectively.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum antibiotic effective against Gram-positive and Gram-negative bacteria
• Treats serious and resistant bacterial infections
• Injectable form ensures rapid therapeutic levels in the bloodstream
• Useful for hospitalized patients or severe infections
• Well-tolerated with a favorable safety profile

Indications

Cefa-4 Injection is indicated for:

• Severe lower respiratory tract infections
• Urinary tract infections, including complicated cases
• Skin and soft tissue infections
• Intra-abdominal infections
• Septicemia and bacteremia
• Febrile neutropenia and immunocompromised patients

Mechanism of Action

Cefepime is a β-lactam antibiotic that:

• Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
• Disrupts cell wall integrity, leading to bacterial lysis and death
• Provides bactericidal action against a broad range of bacteria

Dosage and Administration

• Administered by a healthcare professional via intravenous (IV) or intramuscular (IM) injection
• Usual adult dose: 1–2 g every 12 hours, adjusted based on infection severity and kidney function
• Pediatric dosing is weight-based and determined by a physician
• Dose adjustment required in patients with renal impairment
• Administer slowly for IV injection to reduce local irritation

Side Effects

Common side effects:

• Injection site pain or redness
• Nausea, vomiting, or diarrhea
• Mild headache

Rare side effects:

• Allergic reactions including rash, itching, or anaphylaxis
• Changes in liver or kidney function tests
• Blood disorders such as neutropenia or thrombocytopenia in rare cases

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with a history of penicillin or cephalosporin allergy
• Monitor kidney function during prolonged therapy
• Adjust dose in renal impairment
• Observe for signs of superinfection with prolonged use

Contraindications

• Hypersensitivity to Cefepime, other cephalosporins, or β-lactam antibiotics
• History of severe allergic reactions to penicillin

Storage Instructions

• Store below 30°C in a dry place
• Protect from light
• Keep out of reach of children.