Clacido Injection (1 gm+200 mg)/20 ml (Amoxicillin + Clavulanic Acid)

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Clacido Injection (1 gm + 200 mg)/20 ml is a broad-spectrum antibiotic combination containing Amoxicillin and Clavulanic Acid. This injectable formulation is designed to manage moderate to severe bacterial infections, especially those caused by bacteria that produce beta-lactamase enzymes and are resistant to standard antibiotics.

Clacido Injection is widely used in hospital settings for its rapid onset of action and reliable efficacy. It is particularly useful when oral therapy is not suitable or when immediate treatment is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 20 ml vial contains:

  • Amoxicillin 1 gm (1000 mg)
  • Clavulanic Acid 200 mg

It is provided as a sterile preparation for intravenous (IV) or intramuscular (IM) administration.

Mechanism of Action

This combination works synergistically to eliminate bacterial infections:

  • Amoxicillin:
    • Inhibits bacterial cell wall synthesis
    • Leads to bacterial cell lysis and death
  • Clavulanic Acid:
    • Blocks beta-lactamase enzymes that degrade amoxicillin
    • Extends the antibacterial spectrum of amoxicillin

Together, they effectively target both susceptible and resistant bacteria.

Indications

Clacido Injection is indicated for the treatment of:

  • Respiratory Tract Infections
  • Urinary Tract Infections
  • Skin and Soft Tissue Infections
  • Intra-abdominal Infections
  • Bone and Joint Infections

It is also used in severe infections where oral antibiotics are ineffective or impractical.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

  • Administered intravenously or intramuscularly under medical supervision
  • Dosage depends on patient age, weight, severity of infection, and kidney function
  • Usually given at regular intervals as prescribed by a physician
  • Duration of therapy depends on clinical response

Benefits

Clacido Injection offers several advantages:

  • Broad-spectrum antibacterial coverage
  • Effective against beta-lactamase–producing resistant bacteria
  • Rapid therapeutic effect in severe infections
  • Suitable for hospitalized patients
  • Proven safety and efficacy profile

Possible Side Effects

Common side effects include:

  • Nausea, vomiting, or diarrhea
  • Injection site pain or inflammation
  • Skin rash

Serious but rare effects may include:

  • Severe allergic reactions (anaphylaxis)
  • Liver enzyme elevation or liver dysfunction
  • Antibiotic-associated colitis

Precautions

  • Avoid use in patients with known penicillin or beta-lactam allergy
  • Use cautiously in patients with renal or hepatic impairment
  • Monitor liver and kidney function during prolonged therapy
  • Inform your doctor about other medications to avoid interactions
  • Complete the full prescribed course to prevent resistance

Storage

Store below 25°C, protected from light and moisture. Keep out of reach of children. Follow proper handling instructions after reconstitution.

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Clacido Injection (1 gm+200 mg)/20 ml (Amoxicillin + Clavulanic Acid)
Clacido Injection (1 gm+200 mg)/20 ml (Amoxicillin + Clavulanic Acid)
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