Combiplat Tablet 75 mg + 75 mg contains a combination of Clopidogrel and Aspirin. It is an antiplatelet medicine used to prevent blood clots in patients at risk of cardiovascular events. This dual therapy helps reduce the risk of heart attack, stroke, and other clot-related complications by preventing platelets from sticking together.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredients:
  • Clopidogrel 75 mg
  • Aspirin 75 mg
• Dosage Form: Oral tablet

Mechanism of Action

Clopidogrel inhibits the P2Y12 receptor on platelets, reducing platelet activation and aggregation. Aspirin inhibits cyclooxygenase-1 (COX-1), decreasing thromboxane A2 production, which also reduces platelet aggregation. Together, they provide a synergistic antiplatelet effect, significantly lowering the risk of clot formation.

Indications

Combiplat Tablet is indicated for:

• Prevention of myocardial infarction (heart attack)
• Prevention of ischemic stroke
• Acute coronary syndrome (ACS) management
• Post-angioplasty or stent placement therapy
• Patients at high risk of thrombotic cardiovascular events

Dosage and Administration

• To be taken as directed by a physician
• Usually administered once daily
• Can be taken with or without food
• Should be swallowed whole with water
• Long-term therapy is often required depending on condition

Precautions

• Increased risk of bleeding
• Use with caution in patients with peptic ulcer or bleeding disorders
• Avoid use before surgery unless advised by a doctor
• Not recommended during pregnancy unless clearly necessary
• Inform physician about all other medications being used

Side Effects

Common side effects include:

• Stomach upset
• Easy bruising
• Nosebleeds
• Heartburn

Serious side effects:

• Gastrointestinal bleeding
• Intracranial hemorrhage (rare)
• Severe allergic reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from moisture and light
• Keep out of reach of children

Conclusion

Combiplat Tablet 75 mg + 75 mg (Clopidogrel + Aspirin) is an effective dual antiplatelet therapy used to prevent serious cardiovascular and cerebrovascular events. It helps reduce blood clot formation and should be used under strict medical supervision.