Deroximel DR Capsule 231 mg contains Diroximel Fumarate, a delayed-release oral medication used primarily in the management of relapsing forms of multiple sclerosis (MS). It belongs to the class of immunomodulatory agents and works by reducing inflammation, protecting nerve cells, and slowing disease progression.

This delayed-release formulation ensures optimal absorption in the small intestine while minimizing gastrointestinal side effects commonly associated with similar therapies, offering better tolerability and patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each delayed-release capsule contains:

• Diroximel Fumarate 231 mg

Mechanism of Action

Diroximel Fumarate is rapidly converted in the body to monomethyl fumarate (MMF), its active metabolite. MMF activates the Nrf2 pathway, which:

• Reduces oxidative stress in nerve cells

• Modulates immune system activity to decrease inflammation

• Protects central nervous system tissues from damage

Through these mechanisms, Deroximel DR Capsule helps slow the progression of MS lesions, reduce relapse rates, and improve long-term neurological outcomes.

Indications

Deroximel DR Capsule 231 mg is indicated for:

• Relapsing forms of multiple sclerosis (MS)

• Reducing the frequency of MS relapses

• Slowing the accumulation of physical disability associated with MS

• Long-term management of inflammatory and neurodegenerative effects in MS

Dosage and Administration

• The recommended dose is 231 mg orally twice daily, or as prescribed by a healthcare professional.

• Take on an empty stomach, preferably at least 1 hour before or 2 hours after meals.

• Swallow the capsule whole; do not crush, chew, or open.

• Regular neurological evaluation and laboratory monitoring are recommended to track response and detect potential side effects.

Precautions

• Use with caution in patients with a history of liver disease, kidney impairment, or low blood cell counts.

• May cause flushing, gastrointestinal discomfort, or transient liver enzyme elevation.

• Inform your doctor about all other medications, including supplements, to prevent interactions.

• Not recommended during pregnancy or breastfeeding unless clearly needed and supervised by a healthcare professional.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Flushing or warmth in the face

• Diarrhea, nausea, or abdominal discomfort

• Headache or fatigue

• Increased liver enzymes

Serious but rare effects include allergic reactions, severe liver problems, or decreased white blood cell counts. Regular monitoring is essential.

Storage

• Store below 25°C in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Deroximel DR Capsule 231 mg is a well-tolerated and effective therapy for managing relapsing multiple sclerosis. With its delayed-release formulation, it provides consistent symptom control, reduces relapse rates, and improves quality of life for patients living with MS.