Detrusin LA Capsule 2 mg contains Tolterodine Tartrate 2 mg, a long-acting antimuscarinic agent used in the management of overactive bladder (OAB). Tolterodine works by selectively blocking muscarinic receptors in the bladder muscle, reducing involuntary bladder contractions and increasing bladder capacity. This helps control symptoms such as urinary urgency, frequency, nocturia (nighttime urination), and urge incontinence, significantly improving the quality of life for patients with OAB.

Overactive bladder is a condition in which the bladder muscles contract involuntarily, causing a sudden and urgent need to urinate. It can lead to frequent trips to the bathroom, nighttime disruptions, and, in some cases, involuntary leakage of urine. Detrusin LA Capsule 2 mg provides sustained symptom control throughout the day and night with a convenient once-daily dosing regimen, making it suitable for long-term management of OAB.

The long-acting formulation ensures stable blood levels of tolterodine, providing effective relief from bladder overactivity while minimizing fluctuations that could cause side effects. It is suitable for adults of all ages, with dose adjustments recommended in patients with renal or hepatic impairment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Detrusin LA Capsule 2 mg is indicated for:

• Treatment of overactive bladder (OAB) with symptoms of urgency, frequency, and urge incontinence

• Reduction of nocturia, helping improve sleep quality

• Management of urinary urgency and frequent urination affecting daily activities

Key Benefits

• Controls involuntary bladder contractions, reducing urgency and frequency

• Helps prevent urinary leakage and urge incontinence

• Improves sleep quality by reducing nighttime urination

• Long-acting formulation allows once-daily dosing for convenience and adherence

• Enhances patient comfort, daily functioning, and quality of life

Mechanism of Action

Tolterodine Tartrate, the active ingredient in Detrusin LA, is an antimuscarinic agent that selectively binds to muscarinic M2 and M3 receptors in the bladder detrusor muscle. By blocking these receptors, tolterodine reduces involuntary contractions of the bladder, allowing the bladder to store urine more effectively. This decreases urinary urgency, frequency, and incontinence episodes without significantly affecting bladder emptying.

Dosage and Administration

• The recommended dose for adults is 2 mg once daily, preferably in the morning.

• Capsules should be swallowed whole with water and can be taken with or without food.

• Dose adjustments may be required for patients with severe hepatic or renal impairment as advised by a healthcare professional.

• Consistent daily administration is necessary to achieve optimal symptom control.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use with caution in patients with urinary retention, gastric retention, severe liver or kidney disease, or glaucoma.

• May cause dry mouth, constipation, or blurred vision; monitor patients for these effects.

• Inform your physician about all other medications to avoid potential interactions, especially with other anticholinergic drugs.

• Not recommended for patients with known hypersensitivity to tolterodine or other antimuscarinics.

Possible Side Effects

Detrusin LA Capsule 2 mg is generally well tolerated. Possible side effects include:

• Dry mouth

• Constipation

• Headache

• Blurred vision

• Rarely, dizziness or urinary retention

Most side effects are mild and often subside with continued therapy. Dose adjustments may help reduce unwanted effects.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.