Dialiptin-M Tablet 50 mg+850 mg combines Vildagliptin 50 mg and Metformin Hydrochloride 850 mg, offering a dual-action approach to managing type 2 diabetes mellitus. This combination therapy targets two key mechanisms involved in blood glucose regulation: enhancing insulin secretion and reducing hepatic glucose production. Dialiptin-M is designed for adult patients whose blood sugar levels are not adequately controlled by diet, exercise, or monotherapy with either Vildagliptin or Metformin alone.

Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that prolongs the activity of incretin hormones. These hormones stimulate insulin release in response to meals and suppress glucagon secretion, helping maintain postprandial and fasting glucose levels. Metformin Hydrochloride is a biguanide that decreases glucose production in the liver, improves insulin sensitivity, and enhances peripheral glucose uptake. Together, these agents provide complementary glycemic control, addressing both insulin deficiency and insulin resistance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dialiptin-M Tablet 50 mg+850 mg is indicated for adults with type 2 diabetes mellitus:

• When diet, exercise, and monotherapy are insufficient to achieve adequate glycemic control

• As part of combination therapy with other antidiabetic medications, if required

• For patients who benefit from dual-action therapy addressing both insulin secretion and insulin resistance

This combination is not suitable for type 1 diabetes or diabetic ketoacidosis.

Dosage and Administration

The dosage of Dialiptin-M Tablet 50 mg+850 mg should be individualized by a physician based on the patient’s blood glucose levels, renal function, and clinical response:

• Typically administered once or twice daily with meals to reduce gastrointestinal discomfort

• Swallow the tablet whole with water; do not crush or chew

• Regular monitoring of blood glucose levels is recommended to evaluate effectiveness

• Continue adherence to diet, exercise, and lifestyle modifications to optimize results

It is important to follow the prescribed schedule and not adjust the dose without consulting a healthcare professional.

Precautions

• Contraindicated in patients with hypersensitivity to Vildagliptin, Metformin, or any component of the tablet

• Use with caution in patients with renal or hepatic impairment; renal function should be monitored regularly

• Discontinue therapy temporarily in cases of severe infection, dehydration, or surgery

• Patients should be aware of the risk of hypoglycemia when combined with other antidiabetic agents

• Inform the physician of all ongoing medications and medical conditions to avoid interactions

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dialiptin-M Tablet 50 mg+850 mg is generally well tolerated. Common side effects may include:

• Gastrointestinal disturbances such as nausea, vomiting, or diarrhea

• Mild headache or dizziness

• Hypoglycemia, particularly if combined with sulfonylureas or insulin

• Rare cases of lactic acidosis (associated with Metformin)

Seek immediate medical attention if severe abdominal pain, rapid breathing, unusual fatigue, or allergic reactions occur.

Storage

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Dialiptin-M Tablet 50 mg+850 mg provides a safe and effective dual-action therapy for type 2 diabetes mellitus, helping patients achieve better glycemic control while reducing the risk of long-term complications.