Dicephin Injection 2 gm/vial contains Ceftriaxone Sodium, a third-generation cephalosporin antibiotic widely used for the treatment of severe and life-threatening bacterial infections. It is administered intravenously (IV) or intramuscularly (IM) under the supervision of a qualified healthcare professional. Ceftriaxone is known for its broad-spectrum bactericidal activity and extended half-life, allowing convenient once-daily dosing in many clinical situations.

Ceftriaxone works by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins (PBPs), preventing the formation of a stable bacterial cell wall and leading to the destruction of susceptible organisms. It is effective against a wide range of Gram-positive and Gram-negative bacteria, making it a dependable option in hospital settings for serious infections.

The 2 gm strength is particularly useful in severe infections, deep-seated infections, or conditions requiring higher antibiotic concentrations as determined by the treating physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dicephin Injection 2 gm/vial is indicated for the treatment of infections caused by susceptible microorganisms, including:

• Severe lower respiratory tract infections such as pneumonia

• Complicated urinary tract infections

• Intra-abdominal infections

• Skin and soft tissue infections

• Bone and joint infections

• Septicemia (bloodstream infections)

• Bacterial meningitis

• Pelvic inflammatory disease

• Gonorrhea and other serious infections

It is also used as a prophylactic antibiotic before major surgical procedures to reduce the risk of postoperative infections.

Dosage and Administration

The dosage depends on the severity and type of infection, as well as patient age, body weight, and organ function.

• Adults: Commonly 1–2 gm once daily. In severe infections, the dose may be increased up to 4 gm per day as prescribed by the physician.

• Children: Dosage is calculated based on body weight.

• Neonates: Special dosing adjustments are required.

The vial must be reconstituted with a suitable diluent according to medical guidelines. Administration should be carried out under aseptic conditions by trained healthcare professionals only.

Precautions

• Contraindicated in patients with hypersensitivity to ceftriaxone or other cephalosporins.

• Use cautiously in individuals with a history of severe allergic reactions to penicillins or beta-lactam antibiotics.

• Renal and hepatic functions should be monitored during prolonged treatment.

• Avoid concurrent use with calcium-containing IV solutions in neonates.

• Long-term use may lead to superinfection with resistant organisms.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Dicephin Injection is generally well tolerated. Possible adverse effects include:

• Pain, swelling, or redness at the injection site

• Diarrhea

• Nausea or vomiting

• Rash or hypersensitivity reactions

• Temporary elevation of liver enzymes

Serious allergic reactions are rare but require immediate medical attention.

Storage

Store below 25°C in a cool, dry place, protected from light. Keep out of reach of children. Use reconstituted solution within the recommended time frame.

Dicephin Injection 2 gm/vial provides potent and reliable antibacterial therapy for severe infections when used under appropriate medical supervision.