Dilapress Tablet 6.25 mg contains Carvedilol, a well-established antihypertensive and cardiovascular agent used in the management of high blood pressure and certain heart conditions. Carvedilol is a non-selective beta-adrenergic blocker with additional alpha-1 blocking activity, which helps reduce blood pressure and improve heart function. Dilapress Tablet is designed to provide effective cardiovascular protection while being well tolerated for long-term use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Carvedilol 6.25 mg

Therapeutic Class

Beta-blocker with alpha-blocking activity
Antihypertensive agent

Pharmacology

Carvedilol works by blocking beta-1, beta-2, and alpha-1 adrenergic receptors. The blockade of beta-1 receptors reduces heart rate and myocardial contractility, leading to decreased cardiac workload and oxygen demand. Alpha-1 receptor blockade results in vasodilation, which lowers peripheral vascular resistance and contributes to blood pressure reduction.

Unlike conventional beta-blockers, carvedilol does not cause reflex tachycardia and offers added benefits due to its antioxidant properties. It improves left ventricular function and reduces mortality and hospitalization in patients with heart failure. Carvedilol is well absorbed after oral administration and undergoes extensive hepatic metabolism.

Indications

Dilapress Tablet 6.25 mg is indicated for the treatment of:

• Hypertension (high blood pressure)

• Chronic stable angina

• Mild to severe chronic heart failure (as adjunct therapy)

• Left ventricular dysfunction following myocardial infarction

Regular use helps control blood pressure, reduce the risk of cardiovascular events, and improve overall cardiac performance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• Hypertension: The usual starting dose is 6.25 mg once or twice daily, which may be adjusted according to patient response.

• Heart failure: Initiated at low doses and gradually titrated under close medical supervision.

Dilapress Tablet should be taken with food to reduce the risk of orthostatic hypotension. Dosage adjustments should always be guided by a physician.

Contraindications

Dilapress Tablet is contraindicated in patients with:

• Bronchial asthma or severe chronic obstructive pulmonary disease

• Severe bradycardia

• Second or third-degree heart block

• Cardiogenic shock

• Severe hepatic impairment

• Known hypersensitivity to carvedilol

Precautions and Warnings

• Use with caution in diabetic patients as carvedilol may mask symptoms of hypoglycemia.

• Sudden discontinuation should be avoided; the dose should be tapered gradually.

• Caution is advised in patients with peripheral vascular disease or renal impairment.

• Blood pressure and heart rate should be monitored regularly.

Side Effects

Dilapress Tablet is generally well tolerated. Possible side effects include:

• Dizziness or lightheadedness

• Fatigue

• Bradycardia

• Hypotension

• Gastrointestinal discomfort

Most side effects are mild and tend to resolve with continued use or dose adjustment.

Use in Special Populations

• Pregnancy: Use only if clearly needed and prescribed by a physician.

• Lactation: Caution is advised as carvedilol may be excreted in breast milk.

• Elderly: Dose titration should be done carefully.

Storage

Store in a cool and dry place below 30°C. Protect from light and moisture. Keep out of reach of children.