Dophylin Tablet 400 mg contains Doxophylline, a xanthine derivative used as a bronchodilator for the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions characterized by airway obstruction. This oral tablet formulation provides smooth and sustained relief from bronchospasm and helps improve airflow, making it easier for patients to breathe.

Doxophylline is structurally related to theophylline but is better tolerated with a lower incidence of central nervous system stimulation and cardiac side effects. It works by relaxing the smooth muscles of the airways, reducing inflammation, and improving oxygen delivery to the lungs, thus supporting long-term respiratory health in patients with obstructive airway diseases.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Doxophylline: 400 mg per tablet

Indications

Dophylin Tablet 400 mg is indicated for:

• Bronchial asthma in adults and children (age-specific guidance required)

• Chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema

• Relief of wheezing, shortness of breath, and chest tightness

• Adjunct therapy in reversible airway obstruction

• Long-term management of chronic respiratory conditions to prevent exacerbations

Mechanism of Action

Doxophylline exerts its therapeutic effect through multiple mechanisms:

1. Bronchodilation: Relaxes smooth muscles in the bronchi and bronchioles, reducing airway resistance and improving airflow.

2. Anti-inflammatory effect: Reduces inflammatory mediators in the airways, contributing to decreased swelling and mucus production.

3. Phosphodiesterase inhibition: Increases intracellular cyclic AMP (cAMP) levels, promoting smooth muscle relaxation.

4. Minimal CNS and cardiac stimulation: Compared to theophylline, Doxophylline has fewer excitatory effects, making it safer for long-term use.

These combined actions make Dophylin Tablet effective for controlling symptoms of asthma and other obstructive pulmonary conditions.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual adult dose is 400 mg taken 1–2 times daily, depending on the severity of the condition and physician guidance. Tablets should be swallowed with water, preferably after meals to minimize gastric irritation. Dose adjustments may be required for elderly patients or individuals with renal or hepatic impairment.

Benefits of Dophylin Tablet 400 mg

• Provides effective bronchodilation and relief from airway obstruction

• Improves lung function and oxygenation

• Reduces frequency and severity of asthma and COPD exacerbations

• Well-tolerated with minimal CNS and cardiac side effects

• Convenient oral tablet for long-term management of respiratory conditions

• Supports better exercise tolerance and daily activity in patients with chronic lung disease

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Caution in patients with cardiac disorders, hypertension, or liver/kidney impairment

• Monitor for side effects such as nausea, headache, palpitations, or tremors

• Avoid concomitant use with other xanthine derivatives unless directed by a physician

• Not recommended for pediatric patients below a certain age unless prescribed

• Regular follow-up is advised for patients on long-term therapy

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Bronchodilator / Xanthine Derivative.