Duracef DS Suspension 200 mg/5 ml contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. The “DS” (Double Strength) formulation provides a higher concentration of the active ingredient, making it suitable for moderate to severe infections, especially in pediatric and adult patients requiring stronger antibiotic coverage in liquid form.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Duracef DS Suspension is indicated for the treatment of:

• Upper respiratory tract infections (tonsillitis, pharyngitis, sinusitis)
• Lower respiratory tract infections (bronchitis, pneumonia)
• Otitis media (ear infections)
• Urinary tract infections (UTIs)
• Uncomplicated gonococcal infections
• Typhoid fever caused by susceptible organisms

Mechanism of Action

Cefixime works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). This results in:

• Disruption of bacterial cell wall formation
• Weakening of bacterial structure
• Death of susceptible bacteria
• Effective elimination of infection

It provides broad-spectrum activity against many gram-positive and gram-negative bacteria.

Dosage and Administration

• Dosage depends on age, body weight, and severity of infection
• Usually given once or twice daily as prescribed by a physician
• Shake well before each use
• Measure accurately using a dosing spoon or syringe
• Can be taken with or without food
• Complete the full course even if symptoms improve early

Benefits

• Strong double-strength formulation for better infection control
• Effective against a wide range of bacterial infections
• Suitable for both children and adults
• Easy-to-administer oral suspension
• Helps prevent recurrence and complications of infections

Possible Side Effects

Common side effects may include:

• Diarrhea
• Nausea or vomiting
• Abdominal pain
• Headache
• Skin rash

Rare but serious side effects:

• Severe allergic reactions
• Clostridium difficile-associated diarrhea
• Severe skin reactions

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Not effective against viral infections such as cold or flu
• Use cautiously in patients with penicillin or cephalosporin allergy
• Dose adjustment may be required in kidney impairment
• Always complete the full prescribed course
• Use only under medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Duracef DS Suspension may interact with:

• Anticoagulants (e.g., warfarin)
• Probenecid (may increase Cefixime levels)
• Other antibiotics

Inform your healthcare provider about all medications being taken.

Storage

• Store below 30°C in a cool, dry place
• Protect from light
• Keep tightly closed after use
• Keep out of reach of children.