Duracef Suspension 100 mg/5 ml contains Cefixime Trihydrate, a third-generation cephalosporin antibiotic used for the treatment of various bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to the elimination of infection-causing bacteria. This oral suspension is suitable for pediatric and adult patients who require liquid antibiotic therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Duracef Suspension is indicated for the treatment of:

• Upper respiratory tract infections (tonsillitis, pharyngitis, sinusitis)
• Lower respiratory tract infections (bronchitis, pneumonia)
• Otitis media (middle ear infections)
• Urinary tract infections (UTIs)
• Uncomplicated gonococcal infections
• Typhoid fever (caused by susceptible organisms)

Mechanism of Action

Cefixime works by binding to penicillin-binding proteins (PBPs), which inhibits the synthesis of bacterial cell walls. This results in:

• Disruption of bacterial cell wall formation
• Bacterial cell death
• Effective elimination of susceptible bacteria

It provides broad-spectrum antibacterial activity against many gram-positive and gram-negative organisms.

Dosage and Administration

• Dosage depends on age, body weight, and severity of infection
• Usually given once or twice daily as prescribed by a physician
• Shake well before each use
• Measure using a proper dosing device
• Can be taken with or without food
• Complete the full course of therapy even if symptoms improve

Benefits

• Broad-spectrum antibiotic action
• Effective against respiratory, urinary, and ENT infections
• Convenient oral suspension form
• Suitable for children and adults who prefer liquid formulation
• Helps prevent complications of untreated bacterial infections

Possible Side Effects

Common side effects may include:

• Diarrhea
• Nausea or vomiting
• Abdominal pain
• Headache
• Skin rash

Rare but serious side effects:

• Severe allergic reactions
• Clostridium difficile-associated diarrhea
• Severe skin reactions

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Not effective against viral infections such as cold or flu
• Use cautiously in patients with a history of penicillin allergy
• Dose adjustment may be required in kidney impairment
• Complete the full prescribed course
• Use only under medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Duracef Suspension may interact with:

• Anticoagulants (e.g., warfarin)
• Other antibiotics
• Probenecid (may increase Cefixime levels)

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a dry place
• Protect from light
• Keep bottle tightly closed after use
• Keep out of reach of children.