Esoprex Injection contains Esomeprazole 40 mg per vial, a proton pump inhibitor (PPI) used for the short-term management of acid-related gastrointestinal disorders when oral therapy is not feasible. It works by significantly reducing gastric acid secretion, providing rapid relief from symptoms and promoting healing of the stomach and esophageal lining.

This injectable formulation is typically used in hospital settings for patients who are unable to take oral medications or require immediate acid suppression.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Esoprex Injection is indicated for:

• Gastroesophageal reflux disease (GERD)
• Erosive esophagitis
• Peptic ulcer disease (gastric and duodenal ulcers)
• Prevention and treatment of stress-related mucosal damage
• Management of upper gastrointestinal bleeding (as part of therapy)
• Zollinger-Ellison syndrome
• Patients unable to take oral proton pump inhibitors

Mechanism of Action

Esomeprazole works by suppressing gastric acid production:

• Inhibits the H⁺/K⁺ ATPase enzyme (proton pump) in gastric parietal cells
• Blocks the final step of acid secretion
• Reduces both basal and stimulated gastric acid output
• Promotes healing of ulcers and inflamed esophageal tissue
• Provides effective and sustained acid suppression

Dosage & Administration

• Administered as an intravenous injection or infusion by healthcare professionals
• Usual dose: 40 mg once daily, depending on indication
• Reconstituted before administration as per clinical guidelines
• May be given as slow IV injection or infusion
• Transition to oral therapy is recommended when possible
• Should only be used under medical supervision

Side Effects

Common side effects may include:

• Headache
• Nausea or vomiting
• Abdominal pain
• Injection site reactions
• Diarrhea or constipation
• Dizziness

Rare but serious side effects may include allergic reactions or electrolyte imbalances with prolonged use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use cautiously in patients with liver impairment
• Long-term use requires monitoring for vitamin B12 and magnesium deficiency
• May interact with certain medications (e.g., clopidogrel)
• Not recommended for prolonged use without medical supervision
• Use during pregnancy and breastfeeding only if clearly necessary
• Inform physician about all ongoing medications

Storage

• Store below 25°C in a cool and dry place
• Protect from light
• Do not freeze
• Keep in original packaging
• Keep out of reach of children.