Esoprex MUPS Tablet 20 mg (Esomeprazole (MUPS preparation))

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Esoprex MUPS Tablet contains Esomeprazole 20 mg in a Multiple Unit Pellet System (MUPS) formulation, designed to provide effective and consistent acid suppression. It is widely used in the management of acid-related gastrointestinal disorders, including gastroesophageal reflux disease (GERD), peptic ulcers, and acid dyspepsia.

The MUPS technology allows the tablet to disperse into multiple enteric-coated pellets, ensuring uniform drug release, improved absorption, and better gastric protection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Esoprex MUPS Tablet 20 mg is indicated for:

  • Gastroesophageal reflux disease (GERD)
  • Mild to moderate acid reflux symptoms
  • Erosive esophagitis (maintenance therapy)
  • Gastric and duodenal ulcers
  • Prevention of NSAID-induced ulcers
  • Helicobacter pylori eradication (in combination therapy)
  • Functional dyspepsia (acid-related)

Mechanism of Action

Esomeprazole acts by suppressing gastric acid production:

  • Inhibits the H⁺/K⁺ ATPase (proton pump) in gastric parietal cells
  • Blocks the final step of acid secretion in the stomach
  • Reduces both basal and stimulated acid output
  • Promotes healing of gastric and esophageal mucosa
  • MUPS formulation ensures controlled and uniform release of pellets

Dosage & Administration

  • Usual dose: 20 mg once daily or as prescribed by a physician
  • Should be taken before meals, preferably in the morning
  • Tablet may be swallowed whole or dispersed in water (do not crush pellets)
  • Duration depends on the condition and clinical response
  • Follow physician’s instructions carefully for best results

Side Effects

Common side effects may include:

  • Headache
  • Nausea
  • Abdominal discomfort
  • Diarrhea or constipation
  • Flatulence
  • Dry mouth

Long-term use may be associated with vitamin B12 deficiency, hypomagnesemia, and increased risk of bone fractures.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

  • Use cautiously in patients with liver impairment
  • Long-term therapy should be medically supervised
  • May interact with drugs like clopidogrel and certain antifungals
  • Not recommended for prolonged self-medication
  • Inform physician about all ongoing medications
  • Use during pregnancy and breastfeeding only if prescribed

Storage

  • Store below 25°C in a cool and dry place
  • Protect from moisture and light
  • Keep in original packaging
  • Keep out of reach of children.

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Esoprex MUPS Tablet 20 mg (Esomeprazole (MUPS preparation))
Esoprex MUPS Tablet 20 mg (Esomeprazole (MUPS preparation))
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