Fluclox Injection 500 mg/vial contains Flucloxacillin Sodium, a narrow-spectrum penicillin antibiotic effective against Gram-positive bacteria, especially Staphylococcus aureus, including penicillinase-producing strains. This injectable form ensures rapid therapeutic levels in the bloodstream, making it ideal for moderate to severe infections or when oral administration is not feasible.

Flucloxacillin works by inhibiting bacterial cell wall synthesis, leading to bacterial lysis and rapid resolution of infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluclox Injection is indicated for the treatment of:

• Severe skin and soft tissue infections (cellulitis, abscesses, boils)
• Wound infections
• Bone and joint infections (osteomyelitis)
• Respiratory tract infections (pneumonia, tonsillitis)
• Ear infections (otitis media)
• Prophylactic use in surgeries with risk of Staphylococcus infection

Dosage and Administration

• Administered by intramuscular (IM) or intravenous (IV) injection under medical supervision.
• Adults: 500 mg every 6 hours, depending on infection severity.
• Pediatric doses are calculated based on body weight and clinical condition.
• Reconstitute the vial with sterile water or suitable diluent before administration.
• IV administration should be given slowly; IM injections should be deep into muscle tissue.
• Complete the full prescribed course even if symptoms improve early.

Mechanism of Action

Flucloxacillin is a beta-lactam antibiotic that:

• Binds to penicillin-binding proteins (PBPs)
• Inhibits bacterial cell wall synthesis
• Causes bacterial cell lysis and death

It is particularly effective against penicillinase-producing Staphylococcus aureus, providing rapid and reliable infection control.

Precautions

• Use cautiously in patients with a history of penicillin allergy.
• Monitor liver and kidney function during prolonged therapy.
• Prolonged therapy may result in superinfection by resistant organisms.
• Maintain adequate hydration to prevent kidney complications.

Contraindications

Do not use Fluclox Injection 500 mg in:

• Patients with hypersensitivity to penicillin or other beta-lactam antibiotics
• Individuals with previous severe reactions to Flucloxacillin

Side Effects

Common side effects:

• Pain or irritation at the injection site
• Nausea and vomiting
• Diarrhea
• Skin rash or itching

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, angioedema)
• Liver dysfunction or cholestatic jaundice
• Severe diarrhea due to Clostridium difficile infection

Seek immediate medical attention if serious adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants (e.g., warfarin)
• Probenecid may reduce renal excretion and increase plasma levels
• Live bacterial vaccines may be less effective

Inform your healthcare provider about all medications being taken.

Storage

• Store below 25–30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children
• Use reconstituted solution immediately or as directed by a healthcare professional.