Fosfocin Powder 3 gm/sachet contains Fosfomycin Trometamol, a broad-spectrum antibiotic used to treat urinary tract infections (UTIs) caused by susceptible bacteria. Fosfomycin works by inhibiting bacterial cell wall synthesis, leading to the destruction of bacteria and rapid resolution of infection.

This single-dose oral formulation provides convenient treatment, especially for uncomplicated UTIs in adults, ensuring high concentrations of the drug in the urinary tract with minimal systemic exposure. Fosfocin is particularly effective against Escherichia coli and Enterococcus faecalis, including strains resistant to other antibiotics.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fosfocin Powder is indicated for:

• Uncomplicated urinary tract infections (cystitis) in adult women
• Prophylaxis of urinary tract infections in select cases (as prescribed)
• Infections caused by E. coli, Enterococcus faecalis, and other susceptible bacteria

Dosage and Administration

• Adults: Single-dose therapy, typically 3 gm of Fosfomycin Trometamol.
• Dissolve the contents of one sachet in a glass of water (approximately 100 ml) and drink immediately.
• Take on an empty stomach or at least 2 hours after meals for optimal absorption.
• Ensure adequate hydration to enhance drug excretion and effectiveness.
• Not usually recommended for children unless specifically prescribed by a physician.

Mechanism of Action

Fosfomycin Trometamol is a bactericidal antibiotic that:

• Inhibits the initial step in bacterial cell wall synthesis by blocking the enzyme enolpyruvyl transferase
• Leads to bacterial cell lysis and elimination
• Provides effective treatment against Gram-positive and Gram-negative uropathogens

This action ensures rapid clearance of bacteria from the urinary tract.

Precautions

• Use cautiously in patients with kidney impairment.
• Not recommended in patients with known hypersensitivity to Fosfomycin or related antibiotics.
• May alter the results of certain urine glucose tests; inform laboratory personnel before testing.
• Adequate hydration is important to prevent crystalluria.

Contraindications

Fosfocin Powder should not be used in:

• Patients allergic to Fosfomycin Trometamol
• Individuals with severe renal impairment unless prescribed by a doctor
• Children under 12 years unless specifically advised

Side Effects

Common side effects:

• Diarrhea
• Nausea and vomiting
• Abdominal discomfort
• Headache

Rare but serious side effects:

• Severe allergic reactions (rash, itching, swelling)
• Clostridium difficile-associated diarrhea
• Transient liver enzyme elevation

Seek immediate medical attention if severe or persistent adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with antacids or products containing calcium, magnesium, or aluminum; avoid simultaneous administration.
• Inform your healthcare provider of all medications being taken to prevent interactions.

Storage

• Store below 25°C in a dry place
• Protect from moisture and light
• Keep sachets in their original packaging until use
• Keep out of reach of children.