Gastalfet Tablet 500 mg contains Sucralfate, a well-established gastroprotective agent used for the treatment and prevention of peptic ulcer disease and other acid-related gastrointestinal conditions. This lower-strength formulation is suitable for dose adjustment, maintenance therapy, or patients requiring flexible dosing. Gastalfet Tablet acts locally on the gastric mucosa to promote ulcer healing and provide long-lasting protection against acid and digestive enzymes. 

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Sucralfate 500 mg

• Dosage Form: Oral tablet

Therapeutic Class

• Anti-ulcerant

• Gastrointestinal Mucosal Protectant

Indications

Gastalfet Tablet 500 mg is indicated for:

• Treatment of duodenal and gastric ulcers

• Prevention of ulcer recurrence

• Management of gastritis and gastroduodenitis

• Protection of gastric mucosa in patients receiving NSAIDs

• Relief of symptoms related to acid-induced mucosal injury

It is suitable for both short-term treatment and maintenance therapy as advised by a physician.

Pharmacology

Sucralfate is a complex aluminum salt of sucrose sulfate that exerts its therapeutic effect in an acidic environment. When exposed to gastric acid, it forms a thick, viscous paste that adheres selectively to ulcerated or inflamed areas of the gastrointestinal lining. This protective coating acts as a physical barrier against gastric acid, pepsin, and bile salts. In addition, sucralfate stimulates local prostaglandin and bicarbonate production, enhancing mucosal blood flow and promoting tissue repair. Systemic absorption is minimal, ensuring localized action with a favorable safety profile.

Dosage and Administration

The dosage of Gastalfet Tablet 500 mg should be determined by a healthcare professional based on the clinical condition.

• Usual adult dose: 500 mg to 1 g taken multiple times daily on an empty stomach

• Tablets are usually taken one hour before meals and at bedtime

Treatment duration depends on ulcer severity and response to therapy. Consistent use as prescribed is important for optimal healing. 

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

Gastalfet Tablet is contraindicated in patients with:

• Known hypersensitivity to sucralfate or any formulation components

• Severe renal impairment, due to potential aluminum accumulation

Precautions and Warnings

• Use with caution in patients with kidney disease

• Sucralfate may reduce the absorption of certain medications; a dosing interval of at least 2 hours is recommended

• Constipation is the most commonly reported adverse effect

• Long-term use should be monitored under medical supervision

Use in Special Populations

• Pregnancy: Generally considered safe when prescribed

• Lactation: Use under medical advice

• Elderly Patients: Usually well tolerated; renal function monitoring may be advisable

Storage Conditions

• Store below 30°C in a dry place

• Protect from moisture and heat

• Keep out of reach of children

Presentation

Gastalfet Tablet 500 mg is available in appropriate packaging designed to maintain product quality, ensure accurate dosing, and support patient compliance.