Gastalfet Tablet 500 mg contains Sucralfate, a gastroprotective medication widely used in the treatment and prevention of peptic ulcer disease and other acid-related gastrointestinal disorders. Sucralfate acts locally on the gastric and duodenal mucosa, forming a protective barrier over damaged tissue and promoting natural healing. This 500 mg strength allows flexible dosing and is suitable for both active treatment and maintenance therapy under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Sucralfate 500 mg

• Dosage Form: Oral tablet

Therapeutic Class

• Anti-ulcerant

• Gastrointestinal Mucosal Protectant

Indications

Gastalfet Tablet 500 mg is indicated for:

• Treatment of duodenal ulcers and benign gastric ulcers

• Prevention of ulcer recurrence after healing

• Management of gastritis and gastroduodenitis

• Protection of the gastric mucosa in patients receiving NSAIDs

• Relief of symptoms associated with acid-induced mucosal injury, such as epigastric pain and discomfort

Pharmacology

Sucralfate is a basic aluminum salt of sucrose sulfate that becomes active in an acidic environment. Upon exposure to gastric acid, it forms a viscous, adhesive complex that binds selectively to ulcerated and inflamed areas of the gastrointestinal mucosa. This protective layer acts as a physical barrier against aggressive factors such as hydrochloric acid, pepsin, and bile salts. In addition, sucralfate enhances mucosal defense by stimulating prostaglandin synthesis, increasing bicarbonate secretion, and improving local blood flow. Systemic absorption is minimal, allowing targeted local action with a favorable safety profile.

Dosage and Administration

The dosage of Gastalfet Tablet 500 mg should be individualized according to the patient’s clinical condition and response to therapy.

• Usual adult dose: 500 mg to 1 g taken two to four times daily

• Tablets are preferably taken on an empty stomach, one hour before meals and at bedtime

Patients should follow the prescribed dosing schedule to achieve optimal therapeutic outcomes.

Contraindications

Gastalfet Tablet 500 mg is contraindicated in patients with:

• Known hypersensitivity to sucralfate or any excipients

• Severe renal impairment, due to the risk of aluminum accumulation

Precautions and Warnings

• Use with caution in patients with chronic kidney disease

• Sucralfate may interfere with the absorption of certain medications; other drugs should be taken at least 2 hours apart

• Constipation is the most commonly reported side effect

• Long-term use should be monitored by a healthcare professional

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Generally considered safe when used as prescribed

• Lactation: Use under medical advice

• Elderly Patients: Usually well tolerated; renal function monitoring may be advisable

Storage Conditions

• Store below 30°C in a dry place

• Protect from moisture and heat

• Keep out of reach of children

Presentation

Gastalfet Tablet 500 mg is available in appropriate packaging to ensure product stability, accurate dosing, and patient convenience.