Genib Tablet 250 mg contains Gefitinib. It is an oral anticancer medication primarily used for the treatment of certain types of lung cancer. Unlike traditional chemotherapy, gefitinib specifically targets cancer cell growth pathways, making it a form of targeted therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Gefitinib 250 mg

For oral administration.

Mechanism of Action

Gefitinib works by targeting cancer cell signaling pathways:

• Inhibits the epidermal growth factor receptor (EGFR) tyrosine kinase
• Blocks signals that promote cancer cell growth and division
• Prevents tumor progression and spread
• Particularly effective in cancers with EGFR gene mutations

By targeting specific molecular pathways, it helps control cancer with less damage to normal cells compared to conventional chemotherapy.

Indications

Genib Tablet is indicated for:

• Non-Small Cell Lung Cancer
• Advanced or metastatic lung cancer with EGFR mutation-positive status
• First-line or subsequent therapy depending on clinical condition

Dosage and Administration

• Typically taken once daily or as prescribed by an oncologist
• Swallow tablet whole with water
• Can be taken with or without food
• Take at the same time each day for consistency
• Do not crush or chew the tablet

Benefits

Genib Tablet offers several advantages:

• Targeted therapy with specific action on cancer cells
• Effective in EGFR mutation-positive lung cancer
• Oral administration (no need for IV infusion)
• Generally better tolerated than traditional chemotherapy
• Helps slow disease progression and improve quality of life

Possible Side Effects

Common side effects include:

• Skin rash (acne-like)
• Diarrhea
• Dry skin
• Loss of appetite
• Fatigue

Less common side effects:

• Mouth ulcers
• Nausea
• Eye irritation

Serious side effects (require immediate medical attention):

• Interstitial Lung Disease
• Severe liver toxicity
• Persistent diarrhea leading to dehydration
• Severe skin reactions

Precautions

• Use only under oncology supervision
• Regular monitoring of liver function is required
• Inform doctor of any breathing problems immediately
• Avoid during pregnancy and breastfeeding
• Use effective contraception during treatment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Gefitinib may interact with:

• Antacids or proton pump inhibitors (may reduce absorption)
• CYP3A4 inhibitors or inducers
• Warfarin (increased bleeding risk)

Storage

Store in a cool, dry place below 30°C, protected from moisture and light. Keep out of reach of children.