Glipita Tablet 50 mg contains Sitagliptin, an oral antidiabetic medicine used in the management of type 2 diabetes mellitus. It helps improve blood sugar control in adults when used along with proper diet and regular physical activity. Glipita is especially beneficial for patients who do not achieve adequate glycemic control with lifestyle modification alone or with other antidiabetic agents.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

DPP-4 (Dipeptidyl Peptidase-4) Inhibitor

Pharmacology

Sitagliptin works by selectively inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This enzyme is responsible for the breakdown of incretin hormones such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones, which in turn stimulate glucose-dependent insulin release from pancreatic beta cells and reduce glucagon secretion from alpha cells. This dual action helps lower both fasting and postprandial blood glucose levels without causing significant hypoglycemia.

Indications

Glipita Tablet 50 mg is indicated for:

• Management of type 2 diabetes mellitus in adults

• Use as monotherapy when diet and exercise alone are insufficient

• Use in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin, when appropriate

Dosage and Administration

The usual recommended dose of Glipita Tablet is 50 mg once daily, taken orally with or without food. Dosage adjustments may be required in patients with moderate to severe renal impairment. The exact dose and treatment duration should be determined by a registered physician based on individual patient needs and clinical response.

Benefits and Features

• Effectively improves glycemic control

• Low risk of hypoglycemia when used alone

• Weight-neutral therapy

• Convenient once-daily dosing

• Can be safely combined with other antidiabetic medications

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Renal impairment: Dose adjustment is necessary depending on the severity of kidney dysfunction.

• Elderly patients: Generally well tolerated, but renal function should be monitored.

• Pregnancy and lactation: Use only if clearly needed and prescribed by a physician.

Side Effects

Glipita Tablet 50 mg is generally well tolerated. Some patients may experience:

• Headache

• Nasopharyngitis

• Upper respiratory tract infection

• Mild gastrointestinal discomfort

Serious adverse effects are rare but should be reported to a healthcare professional immediately.

Precautions and Warnings

• Not indicated for type 1 diabetes or diabetic ketoacidosis

• Use with caution in patients with a history of pancreatitis

• Regular monitoring of blood glucose and renal function is advised

Storage

Store in a cool and dry place below 30°C. Protect from light and moisture. Keep out of reach of children.