Glitin M Tablet 2.5 mg + 500 mg is a combination oral antidiabetic medication containing Linagliptin and Metformin Hydrochloride. This formulation is designed to help adults with type 2 diabetes mellitus achieve better blood sugar control. Linagliptin enhances insulin secretion and suppresses glucagon release in a glucose-dependent manner, while Metformin reduces hepatic glucose production and improves insulin sensitivity. Together, they provide complementary mechanisms for effective glycemic management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Linagliptin 2.5 mg
• Metformin Hydrochloride 500 mg
• Dosage Form: Tablet

Indications

Glitin M Tablet is indicated for:

• Type 2 diabetes mellitus in adults
• Patients inadequately controlled with diet, exercise, and single antidiabetic agents
• Combination therapy for improved glycemic control

Mechanism of Action

• Linagliptin: Inhibits the DPP-4 enzyme, prolonging the activity of incretin hormones (GLP-1 and GIP) which stimulate insulin secretion and reduce glucagon release after meals.
• Metformin: Lowers hepatic glucose production, enhances peripheral glucose uptake, and improves insulin sensitivity.

The combination targets both fasting and postprandial blood glucose levels for comprehensive diabetes management.

Dosage and Administration

• Take as prescribed by a healthcare professional.
• Typically administered once or twice daily with meals to reduce gastrointestinal side effects.
• Swallow the tablet whole with water; do not crush or chew.
• Maintain regular blood glucose monitoring.
• Follow diet and exercise recommendations for optimal results.

Benefits

• Effective control of fasting and postprandial blood sugar
• Glucose-dependent action of Linagliptin reduces the risk of hypoglycemia
• Improves insulin sensitivity and reduces liver glucose output
• Convenient combination therapy reduces the number of pills
• Supports weight-neutral or weight-managing effects

Possible Side Effects

Common side effects may include:

• Gastrointestinal disturbances (nausea, diarrhea, abdominal discomfort)
• Headache
• Nasopharyngitis
• Mild hypoglycemia (particularly if combined with other antidiabetics)

Seek immediate medical care if severe side effects occur, such as lactic acidosis or pancreatitis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal or hepatic impairment.
• Not suitable for type 1 diabetes or diabetic ketoacidosis.
• Regular monitoring of kidney function is recommended due to Metformin.
• Inform your doctor about other medications and health conditions.
• Use during pregnancy or breastfeeding only under medical supervision.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.