Glymin XR Tablet 500 mg contains Metformin Hydrochloride in an extended-release (XR) formulation. This design allows the medicine to be released slowly over time, providing smoother blood glucose control and better gastrointestinal tolerability compared to immediate-release forms.

It is commonly prescribed for long-term management of type 2 diabetes mellitus, especially in patients who experience stomach upset with standard metformin.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each extended-release tablet contains:

• Metformin Hydrochloride 500 mg (XR formulation)

For oral administration.

Mechanism of Action

Metformin XR works through the same core mechanisms as standard metformin but with prolonged action:

• Decreases glucose production in the liver
• Improves insulin sensitivity in muscle and fat tissues
• Enhances glucose uptake by cells
• Delays intestinal glucose absorption

The extended-release system provides gradual drug delivery, maintaining steady blood levels throughout the day.

Indications

Glymin XR Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients who require long-term blood glucose control
• Individuals who cannot tolerate immediate-release metformin
• Combination therapy with other antidiabetic medications or insulin

Dosage and Administration

• Usually taken once daily with the evening meal or as prescribed
• Swallow tablet whole; do not crush or chew
• Dose may be gradually increased based on blood glucose response
• Follow doctor’s instructions carefully

Benefits

Glymin XR Tablet offers several advantages:

• Extended-release for smoother glucose control
• Reduced gastrointestinal side effects compared to regular metformin
• Convenient once-daily dosing
• Low risk of hypoglycemia when used alone
• Helps with weight management

Possible Side Effects

Common side effects include:

• Mild nausea
• Diarrhea
• Abdominal discomfort

Less common side effects:

• Metallic taste
• Vitamin B12 deficiency with long-term use

Serious side effects (rare):

• Lactic Acidosis

Precautions

• Take with food to reduce stomach upset
• Do not break or chew the tablet
• Monitor kidney function regularly
• Avoid excessive alcohol consumption
• Inform doctor before imaging procedures using contrast dye

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Drug Interactions

Metformin XR may interact with:

• Alcohol (increased risk of lactic acidosis)
• Iodinated contrast agents
• Diuretics and antihypertensives
• Other antidiabetic drugs

Storage

Store in a cool, dry place below 30°C, protected from moisture and sunlight. Keep out of reach of children.