Graftcept Tablet 500 mg (Mycophenolate Mofetil)

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Graftcept Tablet 500 mg contains Mycophenolate Mofetil. It is a prescription medicine used to suppress the immune system, mainly in patients who have undergone organ transplantation. It helps prevent the body from rejecting the transplanted organ.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

  • Mycophenolate Mofetil 500 mg

For oral administration.

Mechanism of Action

Mycophenolate mofetil works by:

  • Inhibiting an enzyme called inosine monophosphate dehydrogenase (IMPDH)
  • Blocking synthesis of guanine nucleotides required for DNA production
  • Suppressing proliferation of T and B lymphocytes (immune cells)
  • Reducing immune response against transplanted organs

This targeted immunosuppression helps prevent organ rejection.

Indications

Graftcept Tablet is indicated for:

  • Prevention of organ rejection in kidney transplant patients
  • Prevention of rejection in heart transplant patients
  • Prevention of rejection in liver transplant patients
  • Sometimes used in combination with other immunosuppressants

Dosage and Administration

  • Usually taken twice daily or as prescribed by a physician
  • Swallow whole with water, with or without food
  • Take at the same time each day for consistent effect
  • Do not crush or split unless advised
  • Must be used exactly as directed to avoid transplant rejection

Benefits

Graftcept Tablet provides:

  • Effective prevention of organ transplant rejection
  • Helps maintain long-term graft survival
  • Allows lower doses of other immunosuppressants like steroids
  • Improves transplant success rates
  • Well-established use in transplant medicine

Possible Side Effects

Common side effects include:

  • Diarrhea
  • Nausea and vomiting
  • Abdominal pain
  • Headache

Less common side effects:

  • Increased risk of infections
  • Anemia or low white blood cell count
  • Fatigue

Serious side effects:

  • Bone Marrow Suppression
  • Severe infections due to immunosuppression
  • Increased risk of certain cancers (long-term use)

Precautions

  • Use only under strict medical supervision
  • Regular blood tests are required (CBC, liver and kidney function)
  • Avoid exposure to infections due to lowered immunity
  • Not recommended during pregnancy (high risk of birth defects)
  • Use effective contraception during and after treatment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Mycophenolate mofetil may interact with:

  • Antacids containing magnesium/aluminum (reduce absorption)
  • Cholestyramine (reduces drug levels)
  • Acyclovir and similar antivirals
  • Other immunosuppressants

Storage

Store in a cool, dry place below 30°C, protected from moisture and light. Keep out of reach of children.

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Graftcept Tablet 500 mg (Mycophenolate Mofetil)
Graftcept Tablet 500 mg (Mycophenolate Mofetil)
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