Hemadus Tablet 100 mg contains roxadustat, an oral medication used for the treatment of anemia associated with chronic kidney disease (CKD), especially in patients on dialysis and non-dialysis-dependent CKD. It works by stimulating the body’s natural production of red blood cells, helping improve hemoglobin levels and reduce the need for injectable erythropoiesis-stimulating agents.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 100 mg
• Dosage Form: Oral tablet

Mechanism of Action

Roxadustat is a hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. It works by stabilizing hypoxia-inducible factor (HIF), which increases the production of endogenous erythropoietin in the kidneys and liver. It also improves iron metabolism by reducing hepcidin levels, enhancing iron absorption and utilization for red blood cell formation.

Indications

Hemadus Tablet 100 mg is indicated for:

• Anemia due to chronic kidney disease (CKD) in dialysis patients
• Anemia in non-dialysis-dependent CKD patients
• Treatment of reduced hemoglobin levels associated with kidney dysfunction

Dosage and Administration

• Dosage is individualized based on hemoglobin levels and patient response
• Usually taken orally 3 times per week or as prescribed by a physician
• Can be taken with or without food
• Regular hemoglobin monitoring is required during therapy
• Dose adjustments should be done only under medical supervision

Benefits

• Increases hemoglobin levels naturally
• Reduces need for injectable erythropoietin therapy
• Improves symptoms of anemia such as fatigue and weakness
• Enhances iron utilization in the body
• Oral administration improves patient convenience

Possible Side Effects

Common side effects may include:

• Nausea
• Dizziness
• Hypertension (increased blood pressure)
• Headache
• Swelling (edema)

Serious side effects may include:

• Increased risk of blood clots
• Cardiovascular complications
• Severe hypertension
• Liver enzyme abnormalities

Precautions and Warnings

• Regular monitoring of hemoglobin and blood pressure is essential
• Use cautiously in patients with cardiovascular disease
• Not recommended during pregnancy or breastfeeding unless clearly advised
• Iron levels should be checked and corrected if necessary before treatment
• Avoid self-medication; strict medical supervision is required

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Hemadus Tablet 100 mg (Roxadustat) is an advanced oral therapy for managing anemia in chronic kidney disease. By stimulating natural red blood cell production and improving iron utilization, it helps improve hemoglobin levels and reduces anemia-related symptoms when used under proper medical supervision.