Hi-Flow D Capsule 0.4 mg+0.5 mg (Tamsulosin Hydrochloride + Dutasteride)

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Hi-Flow D Capsule is a combination medicine containing Tamsulosin Hydrochloride and Dutasteride, used in the management of benign prostatic hyperplasia (BPH). This dual-action therapy helps improve urinary flow by relaxing prostate and bladder neck muscles while also reducing prostate size over time. It provides both rapid symptom relief and long-term disease control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

  • Tamsulosin Hydrochloride 0.4 mg
  • Dutasteride 0.5 mg

This combination targets both dynamic and structural components of prostate enlargement.


Indications

Hi-Flow D Capsule is indicated for:

  • Benign prostatic hyperplasia (BPH)
  • Lower urinary tract symptoms (LUTS) associated with enlarged prostate
  • Urinary hesitancy, weak stream, and incomplete bladder emptying
  • Nocturia (frequent nighttime urination)
  • Progressive prostate enlargement management

Pharmacological Action

This combination works through dual mechanisms:

  • Tamsulosin: Blocks alpha-1 adrenergic receptors in the prostate and bladder neck, relaxing smooth muscles and improving urine flow
  • Dutasteride: Inhibits 5-alpha reductase enzyme, reducing conversion of testosterone to dihydrotestosterone (DHT), leading to gradual shrinkage of the prostate

Together, they provide rapid symptom relief and long-term reduction in prostate size.


Dosage & Administration

  • Usual dose: 1 capsule once daily after the same meal each day
  • Swallow capsule whole with water
  • Do not crush or chew the capsule
  • Regular use is required for full therapeutic benefit
  • Follow physician’s instructions for duration of therapy

Side Effects

Possible side effects include:

  • Dizziness or light-headedness
  • Decreased libido
  • Erectile dysfunction
  • Ejaculation disorders
  • Breast tenderness or enlargement (rare)
  • Postural hypotension

Contraindications

  • Hypersensitivity to Tamsulosin or Dutasteride
  • Women and children (strictly not indicated)
  • Severe hepatic impairment

Precautions & Warnings

  • May cause dizziness; caution while driving or operating machinery
  • Not recommended for use in women, especially during pregnancy (risk to male fetus)
  • Prostate-specific antigen (PSA) levels may be reduced; interpret with caution
  • Regular prostate monitoring is advised
  • Use cautiously in patients with low blood pressure

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy & Lactation

Not applicable. Women must not handle crushed or broken capsules due to risk of absorption of Dutasteride and potential fetal harm.


Storage

  • Store below 30°C
  • Protect from moisture and heat
  • Keep in original packaging
  • Keep out of reach of children. 

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Hi-Flow D Capsule 0.4 mg+0.5 mg (Tamsulosin Hydrochloride + Dutasteride)
Hi-Flow D Capsule 0.4 mg+0.5 mg (Tamsulosin Hydrochloride + Dutasteride)
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