Hydrogest DS Injection 500 mg/2 ml contains Hydroxyprogesterone Caproate, a synthetic progesterone used in obstetrics and gynecology to support pregnancy and manage progesterone deficiencies. This deep-strength formulation provides a higher dose for cases requiring intensified therapy. Hydroxyprogesterone Caproate helps maintain uterine quiescence, supports the endometrium, and reduces the risk of preterm labor, making it an essential therapy for women at high risk of premature delivery or hormonal imbalance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Hydrogest DS Injection 500 mg/2 ml is indicated for:

• Prevention of preterm birth – In women with a history of spontaneous preterm delivery.

• Progesterone supplementation – To support pregnancy in cases of luteal phase deficiency or threatened miscarriage.

• Management of gynecological disorders – Such as abnormal uterine bleeding or hormonal imbalance caused by progesterone deficiency.

Mechanism of Action

Hydroxyprogesterone Caproate is a synthetic progestogen that:

• Supports the uterine lining – Maintains endometrial stability to help sustain early pregnancy.

• Reduces uterine contractions – Helps prevent premature labor by keeping the uterus relaxed.

• Regulates hormonal balance – Corrects progesterone deficiency, supporting reproductive health and proper menstrual cycles.

Dosage and Administration

• Recommended dose: 500 mg administered intramuscularly, typically once weekly or as prescribed by a healthcare professional.

• Administration: Intramuscular injection, usually into the gluteal region. Should be performed by a trained healthcare provider.

• Monitoring: Regular medical supervision is essential to monitor efficacy and safety, particularly during pregnancy.

Precautions and Warnings

• Pregnancy use: Administer only under medical supervision. Avoid use in cases of unexplained vaginal bleeding.

• Allergy: Not recommended for patients with hypersensitivity to Hydroxyprogesterone Caproate or other progestogens.

• Medical conditions: Exercise caution in women with liver disease, cardiovascular disorders, thromboembolic risk, or history of clotting disorders.

• Injection site reactions: Mild pain, redness, or swelling may occur; proper technique minimizes risk.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Pain, redness, or swelling at the injection site

• Headache or dizziness

• Nausea or mild gastrointestinal discomfort

• Breast tenderness

Rare but serious side effects include blood clots, severe allergic reactions, or significant hormonal disturbances, requiring immediate medical attention.

Storage

Store Hydrogest DS Injection 500 mg/2 ml in a cool, dry place at 2–8°C, protected from light. Do not freeze. Keep out of reach of children.

Conclusion

Hydrogest DS Injection 500 mg/2 ml by SK Pharma is a high-strength progesterone therapy for preventing preterm birth and managing progesterone-related gynecological conditions. It helps maintain uterine stability, supports early pregnancy, and corrects hormonal deficiencies under medical supervision. Proper administration and monitoring ensure safety, efficacy, and optimal outcomes for maternal and fetal health.