Inpen Injection 1 gm/vial contains Meropenem Trihydrate, a broad-spectrum carbapenem antibiotic used for the treatment of severe bacterial infections. It is highly effective against a wide range of Gram-positive, Gram-negative, and anaerobic bacteria, making it a valuable option in hospital settings for serious and life-threatening infections.

Meropenem works by inhibiting bacterial cell wall synthesis, leading to rapid bacterial death. It is commonly used when infections are resistant to other antibiotics or when a broad coverage is required before identifying the exact causative organism.

Inpen Injection is administered by intravenous injection or infusion under strict medical supervision. It is widely used in critical care, emergency, and inpatient settings for its fast and reliable antibacterial action.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Meropenem Trihydrate equivalent to Meropenem 1 gm

Indications

Inpen Injection is indicated for:

• Severe pneumonia (including hospital-acquired pneumonia)
• Intra-abdominal infections
• Complicated urinary tract infections
• Sepsis and septicemia
• Skin and soft tissue infections
• Meningitis
• Gynecological infections
• Empiric therapy in severe bacterial infections

How It Works

Meropenem inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disrupts the formation of the bacterial cell wall, causing cell lysis and death. Its broad-spectrum activity makes it effective against many resistant pathogens.

Dosage & Administration

• Must be administered only by a healthcare professional.
• Given intravenously as bolus injection or infusion.
• Dosage depends on infection severity, renal function, and patient condition.
• Treatment duration is determined by the physician.

Possible Side Effects

Some patients may experience:

• Nausea or vomiting
• Diarrhea
• Headache
• Rash or skin reactions
• Injection site inflammation
• Elevated liver enzymes
• Seizures (rare, especially in high doses or renal impairment)

Seek immediate medical attention if severe allergic reactions or neurological symptoms occur.

Precautions

• Use only under hospital supervision.
• Caution in patients with kidney impairment; dose adjustment may be required.
• Inform the physician about any history of antibiotic allergies.
• Use cautiously in patients with seizure disorders.
• Pregnancy and breastfeeding use only if clearly necessary.
• Avoid self-administration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Inpen Injection may interact with:

• Valproic acid (reduced effectiveness)
• Probenecid (increased meropenem levels)
• Other nephrotoxic or neurotoxic drugs

Always inform healthcare providers about all ongoing medications.

Storage

• Store below 25°C.
• Protect from light and moisture.
• Reconstituted solution should be used as directed by medical staff.
• Keep out of reach of children.