Intamycin Injection 80 mg/2 ml contains Gentamicin Sulfate, a broad-spectrum aminoglycoside antibiotic used for the treatment of serious bacterial infections caused by susceptible organisms. It is formulated for parenteral administration and is commonly used in hospital and clinical settings where rapid and effective antibacterial action is required.

Gentamicin works by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit, leading to bacterial cell death. Its bactericidal activity makes it particularly effective against severe infections, especially those caused by aerobic Gram-negative bacteria.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Gentamicin Sulfate

• Strength: Equivalent to Gentamicin 80 mg per 2 ml ampoule

Therapeutic Class

• Aminoglycoside Antibiotic

Indications

Intamycin Injection is indicated for the treatment of moderate to severe infections caused by gentamicin-sensitive bacteria, including:

• Septicemia and bacteremia

• Lower respiratory tract infections

• Urinary tract infections

• Skin and soft tissue infections

• Intra-abdominal infections

• Bone and joint infections

• Gynecological infections

• Serious neonatal infections

It is also used in combination with other antibiotics for the management of complicated infections and for empirical therapy in critically ill patients.

Dosage and Administration

Intamycin Injection is administered by intramuscular (IM) or intravenous (IV) route. Dosage depends on the severity of infection, patient age, body weight, renal function, and clinical response. Dose adjustments are essential in patients with impaired renal function. Treatment should be initiated and monitored by a qualified healthcare professional.

Pharmacology

Gentamicin exhibits rapid bactericidal action against a wide range of Gram-negative organisms, including Escherichia coli, Klebsiella, Proteus, Pseudomonas aeruginosa, and Enterobacter species. It also has activity against some Gram-positive bacteria, particularly Staphylococcus species, when used alone or in combination therapy.

Precautions and Warnings

• Renal function should be assessed before and during therapy.

• Prolonged use may increase the risk of nephrotoxicity and ototoxicity.

• Therapeutic drug monitoring is recommended for long-term treatment.

• Use with caution in elderly patients and neonates.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Adverse Effects

Possible side effects include nephrotoxicity, ototoxicity, vestibular disturbances, and neuromuscular blockade. Most adverse effects are dose-related and reversible when detected early.

Storage

Store below 30°C in a cool, dry place. Protect from light. Keep out of reach of children.

Use in Special Populations

• Pregnancy: Use only if clearly needed and prescribed by a physician.

• Lactation: Gentamicin is excreted in small amounts in breast milk; caution is advised.