Isozine Tablet 20 mg + 37.5 mg is a combination medication containing Isosorbide Dinitrate and Hydralazine Hydrochloride, designed for the management of heart failure and other cardiovascular conditions. This dual-action formulation helps improve blood flow, reduce cardiac workload, and lower blood pressure, supporting overall heart function and enhancing patient quality of life.

• Isosorbide Dinitrate (20 mg) is a vasodilator that works by relaxing blood vessels, which decreases the heart’s workload and improves oxygen delivery to cardiac muscle. It is particularly effective in reducing angina (chest pain) and managing symptoms of heart failure.
• Hydralazine Hydrochloride (37.5 mg) is a direct-acting arterial vasodilator that lowers systemic vascular resistance, helping to decrease blood pressure and improve cardiac output.

The combination of these two agents provides synergistic cardiovascular benefits, making Isozine ideal for patients with heart failure with reduced ejection fraction (HFrEF), especially in individuals who may not tolerate standard therapy alone.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Improves heart function: Enhances cardiac output and oxygen delivery to the heart.
• Reduces blood pressure: Lowers systemic vascular resistance for better circulation.
• Relieves angina: Helps decrease episodes of chest pain caused by reduced blood flow to the heart.
• Supports heart failure management: Reduces symptoms such as fatigue, shortness of breath, and fluid retention.

Indications

• Heart failure, particularly in patients with reduced ejection fraction
• Management of angina pectoris
• Adjunct therapy for hypertension requiring vasodilation
• Patients intolerant to standard heart failure medications (as directed by a physician)

Dosage and Administration

• Typical dose: As prescribed by a physician, usually 1 tablet 2–3 times daily, with adjustments based on patient response and tolerance.
• Tablets should be taken with water, preferably at the same times each day.
• Regular monitoring of blood pressure, heart rate, and clinical symptoms is recommended during therapy.

Precautions

• Use with caution in patients with severe hypotension, coronary artery disease, or valvular heart disease.
• May interact with other cardiovascular medications; inform your doctor about all current prescriptions.
• Avoid sudden discontinuation; dose adjustments should be gradual under medical supervision.
• Patients should be cautious when standing up quickly, as dizziness may occur due to blood pressure changes.

Possible Side Effects

• Headache, dizziness, or lightheadedness
• Flushing or palpitations
• Nausea or gastrointestinal discomfort
• Rarely, severe hypotension or allergic reactions

Seek medical attention immediately if serious adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool, dry place away from sunlight and moisture.
• Keep out of reach of children.
• Do not use after the expiry date indicated on the packaging.

Isozine Tablet 20 mg + 37.5 mg offers a reliable solution for managing heart failure, reducing angina, and supporting cardiovascular health under proper medical supervision. Its dual-action formulation ensures optimal cardiac function and patient well-being.