Itrakill SB Capsule 65 mg contains Itraconazole, a broad-spectrum antifungal agent used to treat a variety of fungal infections. It belongs to the triazole class of antifungals and works by inhibiting the growth of fungi by disrupting the synthesis of ergosterol, an essential component of fungal cell membranes. This results in increased membrane permeability and ultimately, the death of fungal cells.

Itrakill SB is highly effective in managing superficial and systemic fungal infections, including dermatophytosis, onychomycosis (nail infections), candidiasis, and other opportunistic fungal infections. Its oral capsule form ensures convenient administration with systemic absorption, making it suitable for patients requiring comprehensive antifungal therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Itraconazole 65 mg – a triazole antifungal agent

The capsule also contains excipients that support stability, bioavailability, and ease of administration.

Mechanism of Action

Itraconazole works through the following mechanism:

• Inhibition of fungal cytochrome P450 enzyme (14α-demethylase): Prevents the conversion of lanosterol to ergosterol, a vital component of the fungal cell membrane.

• Disruption of cell membrane synthesis: Lack of ergosterol weakens the fungal cell membrane, causing leakage of intracellular contents.

• Fungistatic and fungicidal action: Depending on the concentration and type of fungus, Itraconazole either inhibits fungal growth or causes fungal cell death.

By targeting ergosterol synthesis, Itrakill SB provides effective treatment for a wide range of fungal infections, including both dermatophytes and yeasts.

Indications

Itrakill SB Capsule 65 mg is indicated for:

• Superficial fungal infections, including tinea corporis, tinea cruris, and tinea pedis

• Onychomycosis (fungal nail infections)

• Oral and esophageal candidiasis

• Systemic fungal infections caused by Aspergillus, Histoplasma, Blastomyces, and other pathogenic fungi

• Prophylaxis in immunocompromised patients at risk of fungal infections

Benefits

• Broad-spectrum antifungal activity

• Effective against both superficial and systemic fungal infections

• Oral capsule form ensures systemic absorption for deeper infections

• Well-tolerated with established safety profile

• Can be used for both treatment and prophylaxis in high-risk patients

Dosage and Administration

• Adults: Typically 65 mg once or twice daily depending on infection type, severity, and physician guidance

• Children: Dose must be adjusted based on body weight and clinical condition

• Administration: Swallow the capsule whole with a full glass of water, preferably after a meal to enhance absorption

• Duration of therapy varies according to infection type; dermatophytic infections may require 2–4 weeks, while onychomycosis or systemic infections may need several months of therapy

Precautions

• Use with caution in patients with liver disease; monitor liver function during prolonged therapy

• Avoid in patients with known hypersensitivity to Itraconazole or other azole antifungals

• May interact with several medications (e.g., statins, anticoagulants, certain antihypertensives); consult a physician before use

• Not recommended during pregnancy or breastfeeding unless prescribed by a healthcare professional

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Itrakill SB Capsule 65 mg is generally well tolerated. Mild to moderate side effects may include:

• Gastrointestinal disturbances: nausea, vomiting, diarrhea, or abdominal pain

• Headache or dizziness

• Rarely, liver enzyme elevation or hepatotoxicity

• Allergic reactions such as rash or pruritus

Medical consultation is recommended if severe or persistent adverse effects occur.

Storage

Store below 30°C in a cool, dry place, away from direct sunlight. Keep out of reach of children.

Itrakill SB Capsule 65 mg provides effective, convenient, and safe antifungal therapy for a wide range of fungal infections, supporting rapid recovery and improved patient outcomes.