Ketalar Injection 50 mg/ml contains Ketamine Hydrochloride, a fast-acting anesthetic agent widely used for induction and maintenance of anesthesia. It is known for producing a unique state called “dissociative anesthesia,” where the patient experiences pain relief, sedation, and amnesia while maintaining protective airway reflexes and spontaneous breathing. This makes Ketalar particularly valuable in emergency procedures, short surgical interventions, and diagnostic procedures.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Ketamine Hydrochloride
• Strength: 50 mg per ml
• Dosage Form: Injectable solution

Mechanism of Action

Ketamine works by blocking N-methyl-D-aspartate (NMDA) receptors in the brain. This action interrupts the transmission of pain signals and produces sedation and memory loss. Unlike many other anesthetics, ketamine stimulates the cardiovascular system rather than depressing it, making it suitable for patients with certain medical conditions.

Indications

Ketalar Injection is indicated for:

• Induction and maintenance of general anesthesia
• Short surgical procedures and diagnostic interventions
• Emergency anesthesia, especially in trauma cases
• Sedation for painful procedures such as burn dressing or fracture reduction
• Use in pediatric anesthesia due to its safety profile
• Adjunct to other anesthetic agents

Dosage and Administration

• Administered intravenously (IV) or intramuscularly (IM) by trained healthcare professionals only
• Dosage depends on patient age, body weight, and medical condition
• Typical IV induction dose: 1–4.5 mg/kg
• Typical IM dose: 6.5–13 mg/kg
• Maintenance doses may be adjusted based on procedural needs

Benefits

• Rapid onset of action
• Provides strong analgesia and sedation
• Preserves airway reflexes and breathing
• Minimal impact on cardiovascular stability
• Useful in both adults and pediatric patients
• Effective in emergency and resource-limited settings

Side Effects

Common side effects may include:

• Increased heart rate and blood pressure
• Nausea and vomiting
• Dizziness or blurred vision
• Emergence reactions (hallucinations, confusion)
• Increased salivation

Rare but serious side effects:

• Respiratory depression (rare at recommended doses)
• Severe psychological reactions
• Allergic reactions

Precautions and Warnings

• Should be used under strict medical supervision
• Caution in patients with hypertension, heart disease, or psychiatric disorders
• May increase intracranial or intraocular pressure
• Avoid in patients with known hypersensitivity to ketamine
• Patients should be monitored during recovery for psychological effects

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly needed and prescribed
• Lactation: Consult a healthcare provider before use
• Pediatrics: Widely used with appropriate dose adjustments
• Elderly: Dose adjustments may be required

Storage

• Store below 25°C
• Protect from light
• Keep out of reach of children.