Keto-A Suppository 100 mg contains Ketoprofen, a non-steroidal anti-inflammatory drug (NSAID) used for the management of pain, inflammation, and fever. This rectal formulation is particularly useful for patients who cannot take oral medications due to nausea, vomiting, or gastrointestinal intolerance. It provides effective systemic relief from moderate to severe pain while reducing inflammation and swelling associated with various conditions.

Ketoprofen is widely used in acute and chronic inflammatory conditions, musculoskeletal disorders, post-operative pain, and other situations requiring rapid or reliable analgesia. The suppository form ensures good absorption and effectiveness, especially when oral administration is not feasible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each suppository contains:

• Ketoprofen 100 mg

The suppository base is designed for smooth rectal insertion and rapid drug release for systemic absorption.

Mechanism of Action

Ketoprofen works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes. These enzymes are responsible for the production of prostaglandins, chemical mediators that play a key role in pain, inflammation, and fever.

By reducing prostaglandin synthesis, Ketoprofen:

• Relieves moderate to severe pain

• Reduces inflammation and swelling

• Lowers fever

• Improves mobility and function in painful conditions

The rectal route allows the drug to bypass some gastrointestinal metabolism, making it suitable for patients with oral intolerance.

Indications

Keto-A Suppository 100 mg is indicated for:

• Acute musculoskeletal pain, including sprains and strains

• Postoperative pain management

• Rheumatoid arthritis and osteoarthritis

• Dysmenorrhea (menstrual pain)

• Fever associated with inflammatory conditions

• Pain associated with trauma or injury

Dosage and Administration

The dosage and frequency should be determined by a physician based on the severity of the condition and patient response. Typically, one suppository (100 mg) once or twice daily may be recommended.

Administration instructions:

1. Wash hands before and after use.

2. Remove the suppository from the wrapper.

3. Insert gently into the rectum, preferably after bowel movement or before bedtime.

4. Lie down for a few minutes to allow proper absorption.

Patients should avoid exceeding the prescribed dose and use the lowest effective dose for the shortest duration necessary.

Benefits

• Provides effective relief from pain and inflammation

• Suitable for patients who cannot tolerate oral medications

• Rapid absorption and systemic effect

• Improves patient comfort in acute and chronic conditions

• Convenient rectal formulation for targeted therapy

Precautions

• Use with caution in patients with gastrointestinal ulcers or bleeding disorders

• Avoid in severe liver, kidney, or heart disease

• Not recommended in the third trimester of pregnancy

• May increase the risk of cardiovascular events with long-term use

• Inform the doctor about all other medications to avoid interactions, especially other NSAIDs or anticoagulants

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Mild rectal irritation

• Nausea or vomiting

• Abdominal discomfort

• Headache or dizziness

Serious but rare side effects may include gastrointestinal bleeding, kidney impairment, allergic reactions, or cardiovascular events. Seek medical attention immediately if severe symptoms occur.

Storage

Store below 30°C in a cool, dry place, away from direct sunlight. Keep out of reach of children. Do not use if the suppository is damaged or discolored.