Ketomar 1 mg Tablet is a potent anti-allergic and anti-asthmatic medication designed to prevent and manage bronchial asthma and various allergic conditions, including rhinitis and conjunctivitis. It belongs to the class of Cromoglycate & related drugs and is particularly effective in stabilizing mast cells, reducing mediator release, and preventing hypersensitivity reactions.

Ketomar works by inhibiting the release of histamine, leukotrienes, prostaglandins, and other chemical mediators from cells involved in type-I allergic responses. Its unique mechanism not only prevents asthmatic attacks but also controls symptoms of allergies, providing sustained relief with minimal sedative effects when used as directed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Ketomar 1 mg is indicated for:

• Prophylactic treatment of bronchial asthma

• Symptomatic management of allergic conditions:

  • Allergic rhinitis

  • Allergic conjunctivitis

It is suitable for adults and children above 2 years under medical supervision.

Therapeutic Class

• Cromoglycate & related drugs

Pharmacology

Ketomar 1 mg exhibits powerful anti-allergic activity through:

• Histamine (H1) receptor blockade

• Mast cell stabilization to prevent degranulation

• Inhibition of platelet-activating factor (PAF)

• Reduction of eosinophil chemotaxis and activation

This dual mechanism makes it effective in preventing asthmatic attacks and controlling allergic reactions while minimizing inflammation and hypersensitivity responses.

Dosage and Administration

Adults:

• 1 mg twice daily with food

• May increase to 2 mg twice daily in severe cases

Children above 2 years:

• 1 mg twice daily with food

• For patients prone to sedation, start with 0.5–1 mg at night for the first few days

Elderly:

• Same as adult dosage or as advised by a physician

Consistency is key for prophylactic efficacy, and prior treatments should be continued for at least two weeks after starting Ketomar to prevent exacerbation of asthma.

Drug Interactions

• Oral antidiabetics: May cause reversible fall in platelet count; combination should be avoided

• CNS depressants: Ketomar may potentiate sedative effects of alcohol, antihistamines, hypnotics, and sedatives

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Known hypersensitivity to Ketotifen or formulation components

• Concurrent use with oral antidiabetics (risk of platelet reduction)

Side Effects

• Drowsiness (common at treatment initiation)

• Dry mouth

• Mild dizziness
  These effects typically resolve spontaneously after a few days.

Precautions and Warnings

• Avoid operating machinery or driving during initial treatment

• Continue previous corticosteroid or ACTH therapy for at least two weeks

• Supplement with antimicrobial therapy in case of intercurrent infections

• Avoid alcohol and sedatives during treatment

Overdose

Symptoms: Drowsiness, confusion, hypotension, bradycardia/tachycardia, dyspnea, convulsions, reversible coma
Management: Supportive and symptomatic treatment

Pregnancy and Lactation

• Not recommended due to insufficient safety data

• Use caution in nursing mothers and avoid chest area application

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.