Levoflox Tablet 750 mg (Levofloxacin Hemihydrate)

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Levoflox Tablet 750 mg contains Levofloxacin Hemihydrate, a potent broad-spectrum fluoroquinolone antibiotic used to treat moderate to severe bacterial infections. Levofloxacin is the L-isomer of ofloxacin and is highly effective against a wide range of Gram-positive and Gram-negative bacteria, including strains responsible for respiratory, urinary, and skin infections.

Levoflox Tablet 750 mg provides a higher dose for more serious infections, such as community-acquired pneumonia, complicated urinary tract infections, acute pyelonephritis, and skin or soft tissue infections. Its oral formulation ensures convenient administration while maintaining strong antibacterial efficacy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Levofloxacin exerts a bactericidal effect by interfering with bacterial DNA synthesis:

  • Inhibition of DNA gyrase and topoisomerase IV: These enzymes are essential for DNA replication, transcription, and repair in bacteria.

  • Prevention of bacterial proliferation: Blocking DNA function leads to cell death.

  • Broad-spectrum activity: Effective against both Gram-positive and Gram-negative pathogens, including resistant strains.

This targeted mechanism reduces bacterial load rapidly, making it suitable for acute and complicated infections.

Indications

Levoflox Tablet 750 mg is indicated for:

  • Community-acquired pneumonia (CAP): Effective against Streptococcus pneumoniae, Haemophilus influenzae, and atypical pathogens like Mycoplasma pneumoniae.

  • Complicated urinary tract infections (cUTI) and pyelonephritis: Treats infections caused by E. coli, Klebsiella species, and other susceptible bacteria.

  • Skin and soft tissue infections: Including cellulitis, abscesses, and wound infections.

  • Other infections: When culture and sensitivity tests show susceptibility to Levofloxacin.

Levoflox 750 mg is recommended when higher antibacterial potency is required for serious or resistant infections.

Dosage and Administration

  • The usual adult dose for serious infections is 750 mg once daily, taken orally with or without food.

  • Tablets should be swallowed whole with a full glass of water; do not crush or chew.

  • Duration of therapy depends on infection severity, typically ranging from 5 to 14 days, or as directed by a physician.

  • Complete the full course to prevent recurrence and minimize antibiotic resistance.

  • Ensure adequate hydration during therapy to prevent kidney complications.

Precautions

Possible Side Effects

Common side effects:

  • Nausea, vomiting, or diarrhea

  • Headache or dizziness

  • Abdominal discomfort

  • Mild insomnia or restlessness

Rare but serious side effects:

  • Tendonitis or tendon rupture

  • Peripheral neuropathy

  • Severe allergic reactions

  • QT interval prolongation

  • Clostridioides difficile-associated diarrhea

Storage

Store below 30°C in a dry place, away from sunlight and moisture. Keep out of reach of children.

Levoflox Tablet 750 mg provides high-potency, broad-spectrum antibacterial therapy, offering effective treatment for serious infections with convenient oral administration, rapid action, and improved patient outcomes under medical supervision.

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Levoflox Tablet 750 mg (Levofloxacin Hemihydrate)
Levoflox Tablet 750 mg (Levofloxacin Hemihydrate)
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