Lipofit Injection 10% is a sterile intravenous fat emulsion used as a source of calories and essential fatty acids in patients who cannot obtain adequate nutrition orally or enterally. It is commonly used in parenteral nutrition (TPN) to support critically ill, surgical, or malnourished patients. This lipid-based formulation helps maintain energy balance and supports overall metabolic function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Intravenous Fat Emulsion 10% (commonly derived from soybean oil or a blend of oils)
• Provides essential fatty acids and calories for parenteral nutrition

Mechanism of Action

Lipofit Injection works by delivering triglycerides directly into the bloodstream. These triglycerides are broken down into fatty acids and glycerol, which are utilized by the body as an energy source. It also provides essential fatty acids necessary for cell membrane integrity, hormone production, and overall metabolic processes.

Indications

Lipofit Injection 10% is indicated for:

• Parenteral nutrition in patients unable to eat or absorb nutrients normally
• Malnutrition or severe protein-energy deficiency
• Postoperative patients requiring nutritional support
• Critical illness requiring intensive nutritional therapy
• Long-term intravenous feeding (total parenteral nutrition, TPN)

Dosage and Administration

• Administered via intravenous infusion under medical supervision
• Dosage depends on patient age, weight, energy requirements, and clinical condition
• Must be infused slowly, either alone or as part of a TPN regimen
• Should not be mixed with incompatible drugs or solutions
• Use aseptic technique during administration

Benefits

• Provides essential calories for energy production
• Supplies essential fatty acids for normal body function
• Supports recovery in critically ill and postoperative patients
• Prevents fatty acid deficiency in long-term parenteral nutrition
• Improves nutritional status when oral intake is not possible

Side Effects

Common side effects may include:

• Mild fever or chills
• Nausea
• Fat overload if administered too rapidly

Serious side effects:

• Fat overload syndrome
• Allergic reactions (rare)
• Liver dysfunction with prolonged use
• Respiratory distress in sensitive patients

Immediate medical attention is required if severe reactions occur.

Precautions and Warnings

• Must be used under strict medical supervision
• Monitor serum triglycerides regularly during therapy
• Use cautiously in patients with liver disease, pancreatitis, or lipid metabolism disorders
• Avoid rapid infusion to prevent complications
• Do not use in patients with severe lipid disorders unless advised by a specialist

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Lipofit Injection may interact with:

• Heparin (may increase lipolysis)
• Insulin (may affect glucose metabolism)
• Certain electrolyte or nutritional additives in TPN

Always ensure compatibility before mixing with other infusions.

Storage

• Store below 25°C
• Do not freeze
• Protect from light
• Shake gently before use if required
• Keep out of reach of children.