Miltefos Capsule 50 mg contains Miltefosine, an oral antiparasitic agent used primarily for the treatment of visceral leishmaniasis (kala-azar) and other protozoal infections. It is the first effective oral therapy for leishmaniasis, offering a convenient alternative to injectable treatments under appropriate medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Miltefosine 50 mg
• Dosage Form: Oral capsule

Indications

Miltefos Capsule 50 mg is indicated for:

• Treatment of visceral leishmaniasis (kala-azar)
• Treatment of cutaneous and mucocutaneous leishmaniasis in selected cases
• Management of certain protozoal infections as advised by a physician

Mechanism of Action

Miltefosine acts by disrupting parasite cell membrane function and inhibiting essential cellular processes, leading to parasite death. Its key actions include:

• Interference with cell membrane phospholipid metabolism
• Induction of apoptosis-like cell death in Leishmania parasites
• Inhibition of parasite growth and replication

Dosage and Administration

• Dose is weight-based and strictly prescribed by a physician
• Usually taken once daily with food to improve absorption and reduce gastrointestinal side effects
• Treatment duration commonly ranges from 28 to 42 days, depending on infection type
• Capsules should be swallowed whole with water

Side Effects

Common side effects:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Loss of appetite

Less common but serious:

• Liver enzyme elevation
• Kidney function changes
• Teratogenic effects (harmful to fetus)

Precautions and Warnings

• Strictly contraindicated in pregnancy due to risk of fetal harm
• Effective contraception is required during treatment and for a period after completion
• Use with caution in patients with liver or kidney impairment
• Regular monitoring of renal and hepatic function is recommended
• Not recommended for unsupervised or incomplete therapy due to risk of resistance

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May increase risk of gastrointestinal side effects with other irritant medications
• Caution when used with drugs affecting liver or kidney function
• Avoid alcohol during therapy to reduce hepatic stress

Storage Conditions

• Store below 25°C
• Protect from moisture and direct sunlight
• Keep out of reach of children.