Minirin Melt Tablet 60 mcg contains Desmopressin Acetate, a synthetic analogue of the natural antidiuretic hormone (ADH), vasopressin. It is primarily used to reduce excessive urine production and to manage conditions related to water balance disorders.

Desmopressin works by increasing water reabsorption in the kidneys, thereby decreasing urine output. The “melt” formulation is a sublingual tablet that dissolves under the tongue without the need for water, offering convenient and accurate dosing—especially suitable for children and patients who have difficulty swallowing conventional tablets.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Reduces excessive urination
  Helps control frequent or high-volume urine production.

• Convenient melt formulation
  Dissolves under the tongue without water, ensuring ease of administration.

• Effective overnight symptom control
  Particularly beneficial for managing nocturnal symptoms.

• Well-established therapy
  Widely used for disorders involving antidiuretic hormone deficiency or imbalance.

Indications

Minirin Melt Tablet 60 mcg is indicated for:

• Primary nocturnal enuresis (bedwetting) in children over 5 years of age.

• Central diabetes insipidus.

• Nocturia associated with nocturnal polyuria in adults (as advised by a healthcare provider).

Treatment should be initiated and monitored by a qualified healthcare professional.

Dosage and Administration

• To be placed under the tongue and allowed to dissolve completely.

• Should not be chewed or swallowed whole.

• Fluid intake should be limited from 1 hour before until at least 8 hours after administration to reduce the risk of water retention and hyponatremia.

• Dosage depends on the indication, patient age, and clinical response.

Follow the prescribing physician’s instructions carefully for safe and effective use.

Mechanism of Action

Desmopressin selectively binds to V2 receptors in the renal collecting ducts. This stimulates water reabsorption, reduces urine production, and concentrates urine. Unlike natural vasopressin, desmopressin has minimal effect on blood vessels, reducing the risk of blood pressure changes.

Safety Information

Contraindications:

• Hyponatremia (low sodium levels).

• Moderate to severe renal impairment.

• Polydipsia (excessive fluid intake).

Warnings and precautions:

• Risk of water retention and hyponatremia if fluid intake is not restricted.

• Monitor serum sodium levels during therapy.

• Use cautiously in elderly patients and those with cardiovascular conditions.

Common side effects may include headache, nausea, abdominal pain, and, in rare cases, low sodium levels.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a dry place, protected from moisture. Keep out of reach of children.