Mobifen Plus Injection combines Diclofenac Sodium 75 mg and Lidocaine Hydrochloride 20 mg in a single 2 ml injection to provide rapid and effective relief from acute pain and inflammation. Diclofenac Sodium, a potent non-steroidal anti-inflammatory drug (NSAID), reduces inflammation and swelling, while Lidocaine Hydrochloride, a local anesthetic, provides immediate pain relief by blocking nerve signals in the affected area. This combination is particularly useful for post-operative pain, musculoskeletal injuries, and other acute pain conditions where quick and sustained analgesia is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Diclofenac Sodium 75 mg
• Lidocaine Hydrochloride 20 mg per 2 ml injection

Mechanism of Action

• Diclofenac Sodium inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins responsible for pain, inflammation, and swelling.
• Lidocaine Hydrochloride blocks sodium channels in nerve membranes, preventing pain signal transmission to the brain and providing rapid local anesthesia.
• The combination ensures both immediate and sustained pain relief with anti-inflammatory effects.

Indications

Mobifen Plus Injection is indicated for:

• Acute musculoskeletal pain, sprains, and strains
• Post-operative pain relief
• Pain due to joint inflammation or injury
• Situations requiring rapid analgesia with anti-inflammatory effects

Dosage and Administration

• Administered by a healthcare professional via intramuscular (IM) or slow intravenous (IV) injection
• Typical adult dose: 1–2 ml as needed, depending on severity of pain and physician’s advice
• Use the lowest effective dose for the shortest duration necessary
• Avoid repeated administration beyond recommended limits to reduce risk of adverse effects

Benefits

• Provides rapid and effective pain relief due to Lidocaine
• Reduces inflammation and swelling due to Diclofenac
• Suitable for acute and post-operative pain
• Combines immediate and sustained analgesic effects
• Convenient single-dose formulation for quick administration

Side Effects

Common side effects:

• Mild pain or irritation at injection site
• Nausea or dizziness
• Temporary headache
• Localized numbness or tingling

Serious side effects (rare):

• Gastrointestinal bleeding or ulceration (Diclofenac)
• Kidney or liver impairment
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Cardiac arrhythmia or hypotension (Lidocaine)

Precautions

• Use with caution in patients with kidney, liver, or gastrointestinal disorders
• Monitor blood pressure and kidney function during treatment
• Avoid in patients with known hypersensitivity to NSAIDs or local anesthetics
• Not recommended in severe heart block or arrhythmias without medical supervision
• Elderly patients may be more susceptible to side effects

Contraindications

• Hypersensitivity to Diclofenac, Lidocaine, or other NSAIDs
• Active gastrointestinal bleeding or ulcer
• Severe renal or hepatic impairment
• Severe cardiac conduction disorders
• Late pregnancy (third trimester)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Anticoagulants (e.g., warfarin) – increased bleeding risk
• Other NSAIDs – increased risk of gastrointestinal complications
• ACE inhibitors or diuretics – may affect kidney function
• Other local anesthetics or antiarrhythmic drugs – monitor for additive effects

Storage

• Store below 30°C
• Protect from light and moisture
• Keep out of reach of children.