Moxibac Injection 400 mg/250 ml contains Moxifloxacin Hydrochloride, a broad-spectrum fluoroquinolone antibiotic used for the treatment of various bacterial infections. It is administered intravenously in hospital settings for moderate to severe infections where rapid and reliable antibacterial action is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Moxifloxacin Hydrochloride 400 mg per 250 ml
• Dosage Form: Intravenous infusion solution

Indications

Moxibac Injection is indicated for the treatment of:

• Community-acquired pneumonia
• Complicated intra-abdominal infections
• Skin and soft tissue infections
• Acute bacterial sinusitis
• Chronic bronchitis exacerbations caused by susceptible organisms

Mechanism of Action

Moxifloxacin is a fluoroquinolone antibiotic that works by:

• Inhibiting DNA gyrase and topoisomerase IV
• Blocking bacterial DNA replication and repair
• Leading to rapid bacterial cell death
• Providing broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria

Dosage and Administration

• Administered as intravenous infusion only
• Standard adult dose: 400 mg once daily
• Infusion should be given over 60 minutes
• Duration of therapy depends on infection type and clinical response
• Switch to oral therapy may be considered when appropriate

Side Effects

Common side effects:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness

Serious side effects:

• QT interval prolongation (heart rhythm disturbance)
• Tendon inflammation or rupture
• Severe allergic reactions
• Liver enzyme elevation

Precautions and Warnings

• Use cautiously in patients with cardiac arrhythmias or QT prolongation risk
• Avoid in patients with history of tendon disorders related to quinolone use
• Not recommended in pregnancy and breastfeeding unless necessary
• Monitor liver function during prolonged therapy
• Use carefully in elderly patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Increased risk of QT prolongation with antiarrhythmic drugs, antipsychotics, and macrolide antibiotics
• Antacids and mineral supplements may reduce absorption (for oral forms)
• Caution with other hepatotoxic drugs

Storage Conditions

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.