Multiparin Injection 25000 IU/5 ml contains Heparin Sodium, a fast-acting anticoagulant used to prevent and treat blood clots. It works by inhibiting key clotting factors in the blood, thereby reducing the formation and extension of thrombi. Heparin is widely used in hospital settings for managing various thromboembolic disorders and for maintaining blood flow during certain medical procedures.

Heparin Sodium enhances the activity of antithrombin III, which inactivates thrombin and factor Xa. This action prevents fibrin formation and stops clot progression without dissolving existing clots.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Rapid anticoagulant effect
  Provides immediate action when administered intravenously.

• Prevents clot formation
  Reduces the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other thromboembolic conditions.

• Supports surgical and procedural care
  Used during cardiac surgery, dialysis, and other procedures requiring anticoagulation.

• Flexible dosing
  Allows individualized dosing based on clinical condition and laboratory monitoring.

Indications

Multiparin Injection 25000 IU/5 ml is indicated for:

• Prevention and treatment of deep vein thrombosis (DVT).

• Management of pulmonary embolism (PE).

• Treatment of acute coronary syndromes.

• Prevention of clotting during hemodialysis and extracorporeal circulation.

• Prophylaxis of thromboembolism in high-risk surgical patients.

Therapy should be initiated and monitored by qualified healthcare professionals.

Dosage and Administration

• Administered by intravenous (IV) injection, continuous infusion, or subcutaneous injection.

• Dosage is individualized according to patient condition, body weight, and coagulation test results (such as aPTT).

• Regular monitoring of coagulation parameters is essential to ensure therapeutic effectiveness and minimize bleeding risk.

• Not intended for intramuscular use due to risk of hematoma.

Use only under strict medical supervision.

Mechanism of Action

Heparin Sodium binds to antithrombin III and enhances its activity. This complex inhibits thrombin (factor IIa) and factor Xa, preventing the conversion of fibrinogen to fibrin and thereby reducing clot formation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety Information

Contraindications:

• Active major bleeding.

• Severe thrombocytopenia.

• History of heparin-induced thrombocytopenia (HIT).

• Hypersensitivity to heparin or pork-derived products.

Warnings and precautions:

• Risk of bleeding, especially in high doses or vulnerable patients.

• Monitor platelet counts to detect heparin-induced thrombocytopenia.

• Use cautiously in patients with recent surgery, hypertension, or bleeding disorders.

Common side effects may include bleeding, injection site reactions, and mild thrombocytopenia.

Storage

Store below 25°C, protected from light. Do not freeze. Keep out of reach of children.