Nabumax Tablet 750 mg contains Nabumetone, a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of pain and inflammation associated with various musculoskeletal and joint disorders. It helps reduce swelling, stiffness, and discomfort, improving joint mobility and daily activity in patients with chronic inflammatory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Nabumetone 750 mg
• Dosage Form: Oral tablet

Indications

Nabumax Tablet 750 mg is indicated for:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Musculoskeletal pain and inflammatory conditions
• Other painful inflammatory disorders as prescribed by a physician

Mechanism of Action

Nabumetone is a prodrug NSAID, converted in the liver to its active metabolite. It works by:

• Inhibiting cyclooxygenase (COX) enzymes
• Reducing production of prostaglandins, which cause pain and inflammation
• Providing relief from pain, swelling, and joint stiffness

Its COX-2 preferential activity may offer improved gastrointestinal tolerability compared to some traditional NSAIDs.

Dosage and Administration

• Usual dose: 750 mg once daily, or as directed by a physician
• May be taken with food to reduce stomach irritation
• Swallow whole with a glass of water
• Dose may be adjusted depending on patient response and condition severity

Side Effects

Common side effects:

• Indigestion or stomach discomfort
• Nausea
• Headache
• Dizziness

Serious side effects:

• Gastrointestinal ulceration or bleeding
• Kidney function impairment
• Liver enzyme elevation
• Allergic reactions (rash, swelling, breathing difficulty)

Precautions and Warnings

• Use cautiously in patients with a history of peptic ulcer or GI bleeding
• Avoid use in severe renal or hepatic impairment
• May increase risk of cardiovascular events with long-term use
• Use lowest effective dose for the shortest possible duration
• Extra caution in elderly patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Increased bleeding risk with anticoagulants (e.g., warfarin)
• Higher GI risk with other NSAIDs or corticosteroids
• May reduce effectiveness of some antihypertensive drugs
• Caution with diuretics and lithium

Storage Conditions

• Store below 25°C
• Protect from moisture and light
• Keep out of reach of children.