Naftol Tablet 50 mg contains Naftopidil, a selective alpha-1 adrenergic receptor antagonist designed to manage benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS). By relaxing the smooth muscles of the prostate and bladder neck, Naftopidil improves urine flow, reduces urinary urgency, and relieves discomfort from an enlarged prostate. Its selectivity for lower urinary tract receptors minimizes systemic effects on blood pressure, making it suitable for long-term management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Naftopidil 50 mg per tablet

Mechanism of Action

Naftopidil works by selectively blocking alpha-1 adrenergic receptors in the prostate, urethra, and bladder neck:

• Relaxes smooth muscles of the lower urinary tract
• Reduces urethral resistance
• Improves urinary flow and decreases bladder outlet obstruction
• Minimizes systemic hypotension due to receptor selectivity

Indications

Naftol Tablet 50 mg is indicated for:

• Benign prostatic hyperplasia (BPH) in adult men
• Relief of lower urinary tract symptoms (LUTS) such as:
  • Difficulty starting urination
  • Weak urine stream
  • Frequent urination or urgency
  • Nocturia (nighttime urination)
• Supportive management of bladder outlet obstruction

Dosage and Administration

• Adults: 1 tablet (50 mg) once daily, preferably after a meal
• Swallow the tablet whole with water; do not crush or chew
• Take at the same time daily for consistent results
• Dose adjustments may be necessary in elderly patients or those with liver/kidney impairment
• Continuous therapy may be required for sustained symptom control

Benefits

• Improves urine flow and reduces urinary retention
• Alleviates symptoms of BPH, including frequency and urgency
• Minimizes risk of low blood pressure due to selective alpha-1 action
• Convenient once-daily dosing ensures better patient compliance
• Enhances quality of life in men with lower urinary tract symptoms

Side Effects

Common side effects:

• Dizziness or lightheadedness
• Headache
• Fatigue or drowsiness
• Mild gastrointestinal discomfort

Rare but serious side effects:

• Orthostatic hypotension (drop in blood pressure when standing)
• Palpitations or irregular heartbeat
• Allergic reactions (rash, swelling, or itching)

Precautions

• Monitor blood pressure in patients with cardiovascular conditions
• Use with caution in liver or kidney impairment
• Avoid driving or operating machinery if dizziness or drowsiness occurs
• Consult a physician if using other antihypertensive medications

Contraindications

• Known hypersensitivity to Naftopidil or any component of the tablet
• Severe liver or kidney disease
• History of orthostatic hypotension or uncontrolled hypotension

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May enhance blood pressure-lowering effects of other antihypertensive drugs
• Use caution with drugs metabolized via CYP3A4
• Avoid concomitant use with other alpha-blockers unless prescribed

Storage

• Store below 30°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children.