Nazolin 0.05% Nasal Spray contains oxymetazoline hydrochloride, a fast-acting topical nasal decongestant that provides effective relief from nasal blockage and congestion. It works by constricting dilated blood vessels in the nasal mucosa, thereby reducing swelling, improving airflow, and promoting sinus drainage. Due to its rapid onset and long duration of action, Nazolin is commonly used in both acute and chronic nasal conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nazolin 0.05% is indicated for the relief of nasal congestion associated with:

• Acute and chronic rhinitis

• Common cold

• Sinusitis

• Upper respiratory allergies

• Hay fever

• Epistaxis (nosebleeds)

It is also used as a nasal decongestant in otitis media to help reduce nasal obstruction and improve middle ear ventilation.

Therapeutic Class

• Nasal Anti-histamine Preparations

• Nasal Decongestants & Other Nasal Preparations

Pharmacology

Oxymetazoline hydrochloride is an imidazoline derivative sympathomimetic amine. It acts directly on α-adrenoceptors without affecting β-adrenoceptors. When applied topically to the nasal mucosa, it produces rapid and prolonged vasoconstriction of arterioles. This reduces local blood flow, decreases mucosal edema, and relieves nasal obstruction. The result is improved nasal airway patency and enhanced drainage of the nasal sinuses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage

Oxymetazoline Nasal Spray (0.05%)

• Adults and children ≥6 years:
  2–3 sprays in each nostril twice daily for 3–5 days

• Elderly:
  No dosage adjustment is required

• Children below 6 years:
  Not recommended

Oxymetazoline Nasal Drops

• Adults and children ≥6 years:
  2–3 drops of 0.05% solution in each nostril twice daily

• Children 2–5 years:
  2–3 drops of 0.025% solution in each nostril twice daily

Administration

Nazolin is for intranasal use only and should not be used for longer than 5 days unless advised by a physician.

Instructions for Nasal Spray Use:

• Remove the dust cover cap

• Tilt the head slightly forward and keep the container upright

• Spray into each nostril as directed

• After use, wipe the spray tip with a clean, soft cloth or tissue

• Replace the dust cover cap

Drug Interactions

Nazolin 0.05% should not be used in patients receiving monoamine oxidase (MAO) inhibitors or within 14 days of discontinuing such therapy.

Contraindications

Nazolin 0.05% is contraindicated in patients with:

• Cardiovascular disease

• Hyperthyroidism

• Prostatic enlargement

• Angle-closure glaucoma

• Known hypersensitivity to oxymetazoline or any component of the formulation

Side Effects

Side effects are usually mild and temporary and may include:

• Local irritation

• Dryness of mouth or throat

• Burning or stinging sensation

• Sneezing

• Increased nasal discharge

Pregnancy and Lactation

The safety of Nazolin 0.05% during pregnancy and lactation has not been fully established. However, it is not considered to pose significant risk when used as directed.

Precautions and Warnings

• Avoid contact with eyes

• Do not use for longer than seven days without medical advice

• Prolonged or frequent use may lead to rebound nasal congestion

Overdose

Overdose may cause local irritation and rebound congestion. Management is symptomatic and supportive.

Storage Conditions

Store below 30°C in a dry place, protected from light. Do not refrigerate or freeze. Keep out of reach of children.