Nirova Capsule 100 mg contains Niraparib, an oral anticancer medication classified as a PARP (poly ADP-ribose polymerase) inhibitor. It is primarily used in the maintenance treatment of certain types of ovarian, fallopian tube, and primary peritoneal cancers. Niraparib helps delay disease progression by targeting cancer cell repair mechanisms, thereby improving long-term outcomes in patients who have responded to platinum-based chemotherapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Niraparib
• Strength: 100 mg per capsule

Mechanism of Action

Niraparib works by inhibiting PARP enzymes, which are involved in repairing damaged DNA in cells. Cancer cells, especially those with defective DNA repair pathways (such as BRCA mutations), rely heavily on PARP for survival. By blocking PARP activity, Niraparib prevents DNA repair, leading to accumulation of DNA damage and ultimately causing cancer cell death.

Indications

Nirova Capsule 100 mg is indicated for:

• Maintenance treatment of adult patients with recurrent epithelial ovarian cancer
• Fallopian tube cancer
• Primary peritoneal cancer
• Patients who have achieved a complete or partial response to platinum-based chemotherapy

Dosage and Administration

• Taken orally, once daily or as prescribed by an oncologist
• Dosage may vary based on body weight, platelet count, and patient tolerance
• Capsules should be swallowed whole with water, with or without food
• Treatment should be continued as long as clinical benefit is observed or until unacceptable toxicity occurs

Benefits

• Helps delay cancer progression and recurrence
• Convenient oral administration
• Targets cancer cells with specific DNA repair defects
• Suitable for long-term maintenance therapy

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Fatigue
• Anemia (low red blood cells)
• Thrombocytopenia (low platelet count)
• Loss of appetite

Serious side effects such as bone marrow suppression or hypertension may occur and require close medical monitoring.

Precautions and Warnings

• Should be used under strict supervision of an oncology specialist
• Regular blood tests are required to monitor blood cell counts
• Use with caution in patients with cardiovascular or liver conditions
• Not recommended during pregnancy or breastfeeding
• Inform your doctor about all medications and medical history

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Nirova Capsule 100 mg is an advanced targeted therapy for the maintenance treatment of certain gynecological cancers. By inhibiting DNA repair in cancer cells, it helps prolong remission and improve patient outcomes when used as part of a comprehensive oncology treatment plan.