Nopain Extra Tablet 75 mg + 200 mcg is a combination medication containing Diclofenac Sodium 75 mg and Misoprostol 200 mcg. It is specially formulated to provide strong anti-inflammatory and analgesic effects while reducing the risk of NSAID-induced gastric ulcers. This combination is particularly useful for patients who require long-term treatment for chronic inflammatory conditions but are at increased risk of gastrointestinal complications.

Diclofenac Sodium is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins responsible for pain, inflammation, and swelling. Misoprostol is a synthetic prostaglandin E1 analogue that protects the stomach lining by increasing mucus and bicarbonate secretion and improving mucosal blood flow. Together, they offer effective symptom relief with enhanced gastric protection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Nopain Extra Tablet 75 mg + 200 mcg is indicated for:

• Osteoarthritis

• Rheumatoid arthritis

• Ankylosing spondylitis

• Chronic inflammatory joint diseases

• Long-term NSAID therapy in patients at risk of gastric or duodenal ulcers

• Patients with a history of NSAID-induced gastrointestinal irritation

This formulation is particularly suitable for individuals who need higher anti-inflammatory doses along with ulcer prevention.

Key Benefits

• Strong pain relief: The 75 mg dose of diclofenac provides enhanced analgesic and anti-inflammatory effects.

• Gastric protection: Misoprostol helps prevent NSAID-related gastric and duodenal ulcers.

• Reduced ulcer risk: Offers safer long-term therapy compared to diclofenac alone.

• Convenient combination: Two essential components in one tablet improve patient compliance.

• Effective for chronic conditions: Supports sustained management of arthritis and inflammatory disorders.

Nopain Extra Tablet helps maintain mobility, reduce stiffness, and improve overall quality of life while minimizing gastrointestinal risks.

Dosage and Administration

• Usually one tablet taken once or twice daily, as prescribed by a physician.

• Take with food and a full glass of water to reduce stomach irritation.

• Swallow the tablet whole; do not crush, split, or chew.

• Use the lowest effective dose for the shortest duration necessary.

• Follow medical advice carefully, especially during long-term therapy.

Precautions

• Contraindicated during pregnancy, as misoprostol can cause uterine contractions and miscarriage. Women of childbearing potential must use effective contraception.

• Use cautiously in patients with cardiovascular disease, liver impairment, kidney dysfunction, or gastrointestinal disorders.

• Avoid use with other NSAIDs or anticoagulants unless directed by a physician.

• Monitor for signs of gastrointestinal bleeding such as black stools or severe abdominal pain.

• Inform your doctor about all current medications and medical history before starting therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Diarrhea or abdominal cramps (more common due to misoprostol)

• Nausea, indigestion, or stomach discomfort

• Headache or dizziness

• Flatulence

Rare but serious adverse effects include gastrointestinal bleeding, allergic reactions, liver enzyme abnormalities, kidney impairment, or cardiovascular events. Seek immediate medical attention if severe symptoms occur.

Storage Instructions

• Store below 25°C in a cool, dry place.

• Protect from light and moisture.

• Keep out of reach of children.

• Do not use after the expiration date printed on the packaging.

Nopain Extra Tablet 75 mg + 200 mcg (Diclofenac Sodium + Misoprostol) provides powerful anti-inflammatory relief with added gastric protection, making it a suitable choice for long-term management of arthritis and inflammatory conditions under proper medical supervision.