Orbas Tablet 20 mg contains Olmesartan Medoxomil, a potent angiotensin II receptor blocker (ARB) used for the management of hypertension (high blood pressure) in adults. Hypertension is a chronic condition that can significantly increase the risk of heart attack, stroke, and kidney disease if left uncontrolled. Orbas Tablet 20 mg helps lower blood pressure by relaxing blood vessels and reducing fluid retention, promoting cardiovascular health and overall well-being.

Olmesartan Medoxomil works by selectively blocking angiotensin II type 1 (AT1) receptors, which play a key role in blood vessel constriction and aldosterone-mediated sodium and water retention. This targeted mechanism helps reduce vascular resistance and blood volume, achieving effective and sustained blood pressure control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Effectively lowers systolic and diastolic blood pressure

• Reduces the risk of cardiovascular complications associated with hypertension

• Supports kidney and heart health in hypertensive patients

• Once-daily dosing for convenient administration and improved adherence

• Well-tolerated with minimal metabolic side effects

• Suitable for long-term management of essential hypertension

Mechanism of Action

Orbas Tablet 20 mg lowers blood pressure by targeting the renin-angiotensin-aldosterone system (RAAS):

1. Angiotensin II Receptor Blockade:

   • Olmesartan selectively blocks AT1 receptors, preventing angiotensin II from constricting blood vessels.

   • Results in vasodilation, reducing peripheral resistance and cardiac workload.

2. Reduction of Aldosterone Secretion:

   • Decreases sodium and water retention, reducing blood volume and further lowering blood pressure.

3. Renal and Cardiovascular Protection:

   • Reduces pressure on blood vessels and kidneys, lowering the risk of hypertensive complications.

   • Helps maintain vascular integrity and kidney function over long-term therapy.

Indications

Orbas Tablet 20 mg is indicated for:

• Essential hypertension in adults

• Patients requiring monotherapy for blood pressure control

• Reducing the risk of cardiovascular events associated with high blood pressure

• Long-term maintenance of stable blood pressure to protect heart and kidneys

Dosage and Administration

• Recommended dose: One tablet once daily, orally, or as prescribed by a healthcare professional.

• Can be taken with or without food, preferably at the same time each day.

• Swallow the tablet whole; do not crush or chew.

• Regular blood pressure monitoring is advised to evaluate response and adjust therapy if necessary.

Precautions and Warnings

• Not recommended for pregnant or breastfeeding women.

• Use caution in patients with renal or hepatic impairment.

• Patients with severe hypotension or hypersensitivity to ARBs should avoid this medication.

• Inform your physician of all medications to avoid potential interactions.

• Avoid abrupt discontinuation, as this may lead to rebound hypertension.

• Monitor kidney function and electrolytes during long-term therapy.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Orbas Tablet 20 mg is generally well-tolerated. Common side effects may include:

• Dizziness or lightheadedness

• Headache

• Fatigue

• Mild gastrointestinal disturbances (nausea, abdominal discomfort)

Rare but serious side effects may include kidney dysfunction, severe hypotension, or allergic reactions. Seek immediate medical attention if severe symptoms occur.

Storage

Store below 30°C in a cool, dry place, away from direct sunlight. Keep out of reach of children.

Orbas Tablet 20 mg provides effective, safe, and long-term control of hypertension, lowering blood pressure, reducing cardiovascular risk, and supporting kidney and heart health through selective angiotensin II receptor blockade.