Othera Tablet 20 mg contains Esomeprazole in a Multiple Unit Pellet System (MUPS) preparation, a proton pump inhibitor (PPI) that reduces gastric acid production. Esomeprazole works by selectively inhibiting the H+/K+ ATPase enzyme in the stomach lining, effectively suppressing gastric acid secretion. Othera is indicated for the treatment and management of acid-related gastrointestinal disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Its MUPS formulation allows it to be swallowed whole or dispersed in water for patients who have difficulty swallowing, without compromising efficacy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Othera Tablet 20 mg is indicated for:

• Symptomatic treatment of gastroesophageal reflux disease (GERD)
• Healing of erosive esophagitis
• Management and prevention of gastric and duodenal ulcers
• Prevention of NSAID-induced gastric ulcers
• Part of Helicobacter pylori eradication therapy in combination with antibiotics
• Treatment of Zollinger-Ellison syndrome and other conditions requiring reduced gastric acid

Mechanism of Action

Esomeprazole, the active ingredient in Othera, acts by:

• Irreversibly inhibiting the H+/K+ ATPase enzyme (proton pump) in gastric parietal cells
• Suppressing basal and stimulated gastric acid secretion
• Providing prolonged acid control throughout the day
• Allowing the esophagus, stomach, and duodenum to heal in acid-related conditions

The MUPS technology ensures rapid disintegration and absorption while maintaining protection from stomach acid.

Dosage and Administration

• Adults: Typically 20 mg once daily, 30–60 minutes before a meal, or as prescribed by a physician
• For patients with difficulty swallowing, the tablet can be dispersed in water and ingested immediately
• Treatment duration depends on the condition; GERD and ulcers may require 4–8 weeks
• Do not crush or chew the tablet if swallowing whole

Benefits

• Effective reduction of gastric acid for relief of heartburn and acid reflux
• Promotes healing of erosive esophagitis and gastric ulcers
• MUPS formulation offers flexible administration for adults and elderly patients
• Supports H. pylori eradication therapy when combined with antibiotics
• Improves overall gastrointestinal comfort and quality of life

Possible Side Effects

Othera Tablet is generally well-tolerated. Common side effects may include:

• Headache
• Nausea, vomiting, or diarrhea
• Abdominal pain or flatulence
• Rare side effects: dizziness, rash, or hypersensitivity reactions

Prolonged use may lead to vitamin B12 deficiency or hypomagnesemia; periodic monitoring may be recommended.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not recommended in patients with known hypersensitivity to esomeprazole or other PPIs
• Use with caution in patients with severe liver impairment
• Inform your doctor of all medications, as PPIs can interact with certain drugs (e.g., clopidogrel, ketoconazole)
• Use under medical supervision during pregnancy or breastfeeding
• Report persistent diarrhea or unusual gastrointestinal symptoms

Storage

• Store below 25°C in a cool, dry place
• Keep the tablet in its original container
• Protect from moisture and light
• Keep out of reach of children.