Oramet-SR Tablet 500 mg contains Metformin Hydrochloride, a widely used oral antidiabetic agent in the management of type 2 diabetes mellitus. This formulation is a sustained-release (SR) tablet, designed to release Metformin gradually over time, providing a steady blood glucose-lowering effect and improving patient compliance with once or twice-daily dosing.

Metformin belongs to the biguanide class of drugs and works by reducing hepatic glucose production, enhancing insulin sensitivity, and increasing peripheral glucose uptake. Unlike other antidiabetic medications, Metformin does not stimulate insulin secretion, which means it rarely causes hypoglycemia when used alone. Oramet-SR combines the proven efficacy of Metformin with the convenience of a sustained-release delivery system for more stable glycemic control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Oramet-SR Tablet 500 mg is indicated for:

• Type 2 diabetes mellitus: For adults and adolescents to achieve and maintain optimal blood glucose levels.

• Combination therapy: Can be used with other oral antidiabetic drugs or insulin when diet, exercise, and monotherapy are insufficient.

• Prediabetes management: Under medical supervision, to reduce the risk of progression to type 2 diabetes.

It is not indicated for type 1 diabetes or diabetic ketoacidosis, which require insulin therapy.

Key Benefits

• Sustained-release formulation: Provides gradual drug release for stable blood sugar control and reduced dosing frequency.

• Effective glycemic management: Lowers fasting and postprandial blood glucose levels.

• Weight-neutral effect: Does not typically cause weight gain; may contribute to modest weight loss.

• Low hypoglycemia risk: Safe for monotherapy when used as directed.

• Convenient dosing: Once or twice-daily dosing improves adherence and patient convenience.

Oramet-SR is particularly suitable for patients who prefer fewer daily doses while maintaining effective diabetes management.

Dosage and Administration

• Adults: Usually 500 mg once or twice daily with meals, as directed by a physician.

• Maximum daily dose generally up to 2,000 mg depending on tolerance and blood glucose response.

• Take the tablet with meals to reduce the risk of gastrointestinal discomfort.

• Do not crush or chew the tablet, as this may alter the sustained-release mechanism.

• Dose adjustments may be required for patients with renal impairment or elderly individuals.

Regular monitoring of blood glucose levels, HbA1c, and kidney function is essential for safe and effective treatment.

Precautions

• Avoid in patients with severe renal or hepatic impairment due to the risk of lactic acidosis, a rare but serious complication.

• Limit alcohol consumption during therapy, as it can increase the risk of lactic acidosis.

• Temporarily discontinue before surgical procedures or imaging studies involving contrast dye, as advised by the physician.

• Inform your doctor about all medications being taken to prevent potential interactions affecting blood sugar control.

• Monitor kidney function and blood glucose regularly throughout treatment.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Oramet-SR Tablet 500 mg is generally well tolerated. Common side effects include:

• Nausea, vomiting, or diarrhea

• Abdominal discomfort or bloating

• Mild metallic taste in the mouth

Rare but serious side effects may include lactic acidosis, particularly in patients with kidney or liver problems. Seek immediate medical attention if symptoms such as rapid breathing, unusual fatigue, muscle pain, or abdominal pain occur.

Storage Instructions

• Store at below 25°C in a cool, dry place.

• Protect from moisture and direct sunlight.

• Keep tablets in their original packaging until use.

• Keep out of reach of children.

• Do not use after the expiration date printed on the packaging.

Oramet-SR Tablet 500 mg (Metformin Hydrochloride) is an effective, safe, and convenient treatment option for managing type 2 diabetes. Its sustained-release formulation ensures stable blood sugar control, improved compliance, and long-term health benefits when combined with proper diet, exercise, and regular monitoring.