Pemetrex Injection 100 mg/4 ml contains Pemetrexed, an antifolate chemotherapy medicine used in the treatment of certain types of cancer. It works by interfering with folate-dependent metabolic processes essential for cancer cell growth and replication. This medication is administered in a hospital setting under strict oncology supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Pemetrexed
• Strength: 100 mg per 4 ml

Mechanism of Action

Pemetrexed inhibits multiple folate-dependent enzymes involved in purine and pyrimidine synthesis. By blocking these pathways, it disrupts DNA and RNA formation in rapidly dividing cancer cells, leading to inhibition of tumor growth and cancer cell death.

Indications

Pemetrex Injection is indicated for:

• Non-small cell lung cancer (NSCLC), especially non-squamous type
• Malignant pleural mesothelioma
• Maintenance therapy in selected lung cancer patients
• Combination chemotherapy regimens as prescribed by an oncologist

Dosage and Administration

• Administered intravenously by healthcare professionals only
• Dosage depends on body surface area, cancer type, and treatment protocol
• Given as part of cyclic chemotherapy regimens
• Must be used under strict oncologist supervision

Benefits

• Slows growth and spread of cancer cells
• Effective in lung cancer and mesothelioma treatment
• Can be used in combination or maintenance therapy
• Helps improve progression-free survival in selected patients
• Part of standard modern chemotherapy regimens

Possible Side Effects

Common side effects may include:

• Fatigue
• Nausea and vomiting
• Loss of appetite
• Mouth ulcers
• Low blood counts (anemia, neutropenia, thrombocytopenia)
• Skin rash

Serious side effects may include severe bone marrow suppression and infection risk.

Precautions and Warnings

• Must be used only under oncology supervision
• Regular blood count and liver/kidney function monitoring is required
• Folic acid and vitamin B12 supplementation may be required as per protocol
• Not recommended during pregnancy or breastfeeding
• Use caution in patients with kidney impairment
• Inform doctor about all current medications

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool and dry place
• Protect from light
• Do not freeze
• Keep out of reach of children

Conclusion

Pemetrex Injection 100 mg/4 ml (Pemetrexed) is an antifolate chemotherapy agent used in the treatment of lung cancer and mesothelioma. It works by blocking cancer cell DNA synthesis and is administered under strict medical supervision as part of oncology treatment protocols.